急性一氧化碳中毒患者同型半胱氨酸与迟发性脑病的相关性研究  

Research on the correlation between homocysteine and delayed encephalopathy in patients with acute carbon monoxide poisoning

作　　者：吐亚[1] 李桂花[1] 

机构地区：[1]石河子大学医学院第一附属医院高压氧科,新疆石河子832008

出　　处：《包头医学院学报》2015年第10期4-5,共2页Journal of Baotou Medical College

摘　　要：目的:观察急性一氧化碳中毒患者血清同型半胱氨酸水平的不同,探讨其与迟发性脑病的关系。方法:选取急性一氧化碳中毒患者200例,根据是否发生迟发性脑病将患者分组,35例迟发性脑病患者为观察组,165例无迟发性脑病患者为对照组,应用酶联免疫分析法比较两组患者血浆同型半胱氨酸水平。结果:观察组的血浆同型半胱氨酸水平高于对照组,差异有统计学意义(P<0.05)。结论:急性一氧化碳中毒发生迟发性脑病患者血浆同型半胱氨酸的水平升高,其含量可以作为急性一氧化碳中毒患者出现迟发性脑病的一个预测性指标。Objective：To observe the homocysteine levels in patients with acute carbon monoxide poisoning and explore its relationship with delayed encephalopathy.Methods：200cases of acute carbon monoxide poisoning were selected and divided into the observation group with delayed encephalopathy（35cases）and the control group with non-delayed encephalopathy（165cases）,according to whether there is delayed encephalopathy.Plasma homocysteine levels in the two groups were compared using enzyme-linked immunoassay.Results：Plasma homocysteine levels in the observation group were obviously higher than those in the control group,and there was statistically significant difference between the two groups（P〈0.05）.Conclusion：The plasma homocysteine levels in patients with delayed encephalopathy who suffered from acute carbon monoxide poisoning are elevated,whose content can be used as a predictive index in those patients.

关 键 词：急性一氧化碳中毒 同型半胱氨酸 迟发性脑病 

分 类 号：R595.1[医药卫生—内科学] R747.9[医药卫生—临床医学]