慢性乙型肝炎和慢性丙型肝炎门诊患者生存质量及影响因素分析  

Quality of life and its influential factors in outpatients with chronic hepatitis B or C

作　　者：贾莹[1] 李晓光[1] 李璐[1] 梁京津[1] 康永峰[1] 林菲[1] 邓忠华[1] 王伟[1] 张碧莹[1] 胥婕[1] 

机构地区：[1]北京大学第三医院感染疾病科,北京100191

出　　处：《临床肝胆病杂志》2015年第10期1695-1698,共4页Journal of Clinical Hepatology

基　　金：国家科技支撑计划(2009BA177B04)

摘　　要：目的了解门诊慢性乙型肝炎和慢性丙型肝炎患者的生存质量及其影响因素。方法选取2012年3月-2014年3月在北京大学第三医院门诊就诊的慢性乙型肝炎和慢性丙型肝炎患者为肝炎组,选择同期无明显躯体及精神症状随同患者就诊的家属和进行体检的健康志愿者为对照组,采用SF-36、CLDQ和SSRS量表对肝炎组和对照组进行问卷调查。计量资料组间比较采用成组t检验,计数资料组间比较采用χ2检验,采用多元线性回归分析探讨影响生存质量的相关因素。结果 SF-36量表中肝炎组的生理职能、一般健康状况、精力、社会功能、情感职能、精神健康均低于对照组(P值均<0.05);CLDQ量表中肝炎组的系统症状、情感、焦虑均低于对照组(P值均<0.05)。SSRS调查发现肝炎组的客观支持、主观支持、对支持的利用度及总分均低于对照组(P值均<0.05)。多元线性回归分析得出影响肝炎患者生存质量的主要因素有年龄、性别、职业、婚姻状况、经济收入、社会支持中的主观支持和对支持的利用度等。结论门诊慢性乙型肝炎和慢性丙型肝炎患者的生存质量明显下降。年龄大、女性、离异、农民、经济收入低、主观支持少和对支持的利用度低的患者更需要关注其生存质量,医务人员应该给予患者个体化的健康指导。Objective To study the quality of life（ Qo L） and its influential factors among outpatients with chronic hepatitis B or C. Methods Patients diagnosed with chronic hepatitis B or C between March 2012 and March 2014 were included in the hepatitis group,whereas volunteers presenting with neither significant physical nor mental diseases,who accompanied visiting patients or underwent physical examination,were involved in the control group. A survey using the Short Form- 36（ SF- 36） Chinese version,the Chronic Liver Disease Questionnaire（ CLDQ）,and the Social Support Rating Scale（ SSRS） were performed within the above groups. Results The SF- 36 scores of the hepatitis group were significantly lower than those of the control group in physical role,general health,vitality,social functioning,emotional role,and mental health（ P〈0. 05）. The CLDQ scores of the hepatitis group were significantly lower than those of the control group in systemic symptoms,role emotion,and anxiety（ P〈0. 05）. The hepatitis patients displayed significantly lower scores in all four scales of SSRS（ P〈0. 05）. Multivariable linear regression analysis showed that age,sex,occupation,marital status,income,subjective support,and social support utilization significantly influenced the Qo L among hepatitis patients. Conclusion The Qo L of outpatients with chronic hepatitis B or C is poor. The Qo L of patients showing the characteristics of old age,female sex,divorce,farmer,lower income,less subjective support,and poor social support utilization require more attention to their Qo L. Medical workers should provide proper individualized health guidance for those patients.

关 键 词：肝炎 乙型 慢性 肝炎 丙型 慢性 健康调查 社会支持 

分 类 号：R512.62[医药卫生—内科学]