PM2.5对血压的影响  

Study on the PM2. 5 Influence on Blood Pressure

作　　者：徐建辉[1] 何荣华[1] 

机构地区：[1]孝感市中心医院心血管内科,湖北孝感432000

出　　处：《医学综述》2015年第20期3710-3713,共4页Medical Recapitulate

摘　　要：近年来随着空气质量下降,人们更加重视环境污染的危害性。相关研究表明,空气污染物(主要是PM2.5)与心血管疾病关系密切。PM2.5会增加心血管疾病的发病率和病死率。心血管疾病如高血压,血栓形成,血管功能障碍,动脉粥样硬化,心肌梗死和心脏自主调节功能紊乱等也被认为与空气污染物有关。PM2.5对血压影响的确切机制尚不清楚,其可能机制是PM2.5通过直接作用、氧化应激、炎症及自主神经系统功能失调,继而导致血管舒缩功能受损,最终引起血压的变化。In recent years, with the air quality getting worse, people pay more attention to the harmful- hess of environmental pollution which damages our health. Related studies have shown that air pollutants （ mainly PM2.5 ） is closely related to cardiovascular disease. PM2.5 can increase the morbidity and mortality of cardiovascular diseases. Cardiovascular diseases such as hypertension, thrombosis, vascular dysfunction, atherosclerosis, myocardial infarction and cardiac autonomic regulation dysfunction are considered to be related to air pollutants as well. The exact mechanism of the impact of PM2.5 on blood pressure is unclear, and the potential mecharfisms may be PM2.5 direct function, oxidative stress/systemic inflammation and dys- function of the autonomic nervous system, which in turn lead to impaired vasomotor function, and ultimately affect the blood pressure.

关 键 词：血压 PM2.5 氧化应激/炎症 自主神经 

分 类 号：X513[环境科学与工程—环境工程] R54[医药卫生—心血管疾病]