磁共振扩散加权成像在脑泡型包虫病和高级别脑胶质瘤鉴别诊断中的应用  

The application of diffusion weighted magnetic resonance imaging in the differential diagnosis between cerebral alveolar echinococcosis and high-grade gliomas

作　　者：姜春晖[1] 陈宏[1] 王俭[1] 马娟[1] 依巴努.阿不都热合曼 刘文亚[1] 柳琛[2] 

机构地区：[1]新疆医科大学第一附属医院影像中心,乌鲁木齐830054 [2]新疆医科大学第一附属医院神经外科,乌鲁木齐830054

出　　处：《新疆医科大学学报》2015年第11期1335-1338,共4页Journal of Xinjiang Medical University

基　　金：国家自然科学基金(30860268);新疆维吾尔自治区自然科学基金(2011211A072)

摘　　要：目的探讨磁共振扩散加权成像技术（DWI）在脑泡型包虫病与高级别脑胶质瘤鉴别诊断中的应用价值。方法选择2009—2015年及2013—2014年在新疆医科大学第一附属医院分别确诊为脑泡型包虫病患者11例（有效病灶23个）及高级别（WHOⅢ-Ⅳ级）的脑胶质瘤患者20例（有效病灶20个）;应用3.0T磁共振仪,分别对患者进行全脑常规MR平扫、增强扫描及DWI检查。分别测量病灶实质区、水肿区（病灶周边0-10mm范围水肿区）及对照区（对侧相应部位的正常脑实质区）的表观扩散系数（ADC）值,并进行统计学分析。结果脑泡型包虫病与高级别脑胶质瘤实质区ADC值比较,差异有统计学意义（t=-5.593,P〈0.01）,胶质瘤实质区的ADC值大于脑泡型包虫病实质区;脑泡型包虫病与高级别脑胶质瘤水肿区ADC值比较差异有统计学意义（t=-2.825,P〈0.01）,胶质瘤水肿区的ADC值大于脑泡型包虫病水肿区。结论 DWI与常规MRI联合应用,可为脑泡型包虫病与高级别脑胶质瘤的诊断及鉴别诊断提供有价值的信息。Objective To discuss the application value of Diffusion Weighted Imaging（DWI）in differential diagnosis of Cerebral Alveolar Echinococcosis（CAE）and High-grade Cerebral Glioma.Method 15 cases diagnosed of CAE and High-grade（WHO gradeⅢ-Ⅳ）from 2009 to 2015and 2013 to 2014in The First Teaching Hospital of Xinjiang Medical University were collected respectively.All brain regular MR scan,enhanced scan and DWI were performed on patients with 3.0T MRI.Apparent Diffusion Coefficient（ADC）value of the focal area,edema area（0-10 mm around the focal area）and control area（the offside normal area）were measured respectively and analyzed statistically.Results The ADC value comparison between CAE and high-grade Cerebral Glioma shows statistic significance（t=-5.593,P 〈0.01）with ADC of Cerebral Glioma focal area higher than that of CAE.Statistic significance is also found in the ADC comparison between edema areas of CAE and high-grade Cerebral Glioma（t=-2.825,P〈 0.01）with edema area of Cerebral Glioma higher than that of CAE.Conclusion The combination of DWI and regular MRI provides valuable information in differential diagnosing CAE and High-grade Cerebral Glioma.

关 键 词：脑泡型包虫病 高级别胶质瘤 磁共振扩散加权成像 表观扩散系数 

分 类 号：R445.2[医药卫生—影像医学与核医学]