部分钩突切除对颈椎稳定性影响的有限元分析  

Finite element analysis on the effects of uncinate process resection on the stability of cervical spine

作　　者：薄雪峰[1] 陈赞[2] 王辉[1] 钱秀清[1] 张昆亚[1] 宋红芳[1] 刘志成[1] 

机构地区：[1]首都医科大学生物医学工程学院,北京100069 [2]首都医科大学宣武医院神经外科,北京100053

出　　处：《北京生物医学工程》2015年第5期447-453,共7页Beijing Biomedical Engineering

基　　金：国家自然科学基金(10802053);北京市自然科学基金(3122010);北京市属市管高校人才强教计划资助项目(PHR201110506);北京市人才强教深化计划-中青年骨干人才培养计划(11350312);北京市科技新星培养计划(2007A076);首都医科大学基础临床科研合作基金(1000172005)资助

摘　　要：目的建立颈椎(C4-C6)三维有限元模型,研究钩突切除前后对颈椎稳定性的影响。方法根据健康志愿者的颈椎断层CT扫描序列图像,采用Mimics13.1和Solid Works2012软件进行三维重建和造型,利用ANSYS15.0软件,对颈椎及周围组织赋予不同的材料属性,建立颈椎(C4-C6)三维有限元模型。在建立的模型上加载,模拟脊柱的前屈、后伸、左右侧曲、左右旋转6种工况下的生理活动,获取位移、应力等数值云图,并进行分析验证。在C5节段左侧钩突上分别切除钩突高度的25%、50%和60%,获得不同范围钩突切除时的左侧弯状态下颈椎各部位的位移、应力等数值云图,分析不同范围钩突切除对颈椎稳定性的影响。结果本研究建立了三个椎体运动节段的三维有限元模型,模型高度模拟颈椎结构与材料特性,研究了不同范围钩突切除后,颈椎稳定性受到的影响。钩突切除高度的25%后的左侧弯状态与未切除时对比分析,位移云图变化不大,最大等效应力减小。钩突切除高度的50%、60%后的左侧弯状态下的位移继续增大,最大等效应力逐渐减小。结论切除钩突高度的25%时对颈椎稳定性影响不大,随着切除钩突范围的增加,颈椎的稳定性逐渐降低。Objective We established a three-dimensional finite element model of the cervical spine（ C4-C6） to study uncinate process resection effects on the stability of cervical spine. Methods A threedimensional finite element model of the cervical spine was established from the CT scan images of a healthy male using Mimics13. 1, Solid Works2012, and ANSYS15. 0 software. Different materials were assigned different mechanical parameters,and we created a cervical three-dimensional finite element model based on the method of tetrahedral mesh. Loading in the established model to simulate the extension,flexion,lateral bending,rotation,the total deformation and equivalent stress of spine were obtained and verified. The left uncinate process was resected 25%, 50% and 60%respectively in the C5 section. We analyzed the effects of uncinate process resection of different range on the stability of cervical spine in left lateral bending. Results The three-dimensional finite element model with more structure integrity and geometric similarity was compartmentalized subtly. Through comparative analysis ofuncinate process resection： 25%,50%,60% compared with non resection,total deformation increased and the maximum equivalent stress decreased along with the increasing range of uncinate process resection.Conclusions The 25% resection of the uncinate process had little effect on the stability of cervical vertebrae.With the increase of uncinate process resection,the stability of the cervical spine decreased.

关 键 词：颈椎稳定性 钩突切除 有限元模型 

分 类 号：R318.04[医药卫生—生物医学工程]