脂肪干细胞治疗下肢缺血的研究进展  

Progress in Researches of Adipose-derived Stem Cells for Hind-limb Ischemia

作　　者：袁福康[1,2] 秦金保[1,2] 叶开创[1,2] 彭智猷[1,2] 杨心蕊[1,2] 黄丽佳[1,2] 陆信武[1,2] 

机构地区：[1]上海交通大学医学院附属第九人民医院血管外科 [2]上海交通大学血管病诊治中心,上海200011

出　　处：《现代生物医学进展》2015年第28期5598-5600,5427,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(81370423);上海市科学技术委员会项目(134119a2100)

摘　　要：下肢缺血性疾病是临床常见的严重危害中老年人健康的疾病之一。目前,临床针对下肢缺血性疾病的治疗方法多样,但远期疗效欠佳,对于肢体严重缺血的患者往往需要进行截肢处理。脂肪干细胞(adipose-derived stem cells,ADSCs)作为再生医学用于治疗下肢缺血的种子细胞具有广阔的应用前景。本文将对ADSCs治疗下肢缺血的研究进展进行综述。Lower-limb ischemia has become an increasingly serious hurtful health problem in middle aged and elderly people. At present, there are kinds of treatment methods of lower limb ischemic disease, but the long-term follow-up＇s result is terrible, for patients with severe limb ischemia often have to take the amputation surgery. ADSCs as seed cells exhibit tremendous promise for regenerative repair of hind-limb ischemia.Therefore,this review is mainly focusing on the recent progress on ADSCs for hind-limb ischemia.

关 键 词：脂肪干细胞 下肢缺血 移植 分化 细胞治疗 

分 类 号：R654.4[医药卫生—外科学]