胸大肌肌瓣转移术预防乳腺癌术后上肢淋巴水肿的临床研究  

Clinical Research of the Pectoralis Major Myocutaneous Flap Transfer in the Prevention of Breast Cancer-related Lymphedema after Modified Radical Mastectomy

作　　者：王颖[1] 陈飞[1] 孙鹤庆[1] 路选[1] 

机构地区：[1]扬州市第一人民医院乳腺外科,江苏省扬州市225001

出　　处：《组织工程与重建外科杂志》2015年第5期313-315,共3页Journal of Tissue Engineering and Reconstructive Surgery

摘　　要：目的探讨胸大肌肌瓣转移术对乳腺癌改良根治术后患侧上肢淋巴水肿的预防效果。方法自2013年9月至2014年6月,将68例乳腺癌患者分成2组,35例行乳腺癌改良根治术+胸大肌肌瓣转移术(干预组),33例单纯行乳腺癌改良根治术(对照组),术后随访观察,分别在术后2周、1个月、3个月、6个月和9个月测量双侧臂围,判断有无上肢淋巴水肿的发生及程度。结果随访结果表明,干预组和对照组相比,术后患侧上肢淋巴水肿发生率明显减少,差异具有统计学意义(P<0.05)。结论乳腺癌改良根治术后行胸大肌肌瓣转移术,可显著减少乳腺癌术后患侧上肢淋巴水肿的发生率,提高患者的生活质量。Objective To investigate the clinical effect of Pectoralis major myocutaneous flap transfer on the prevention of breast cancer-related lymphedema after modified radical mastectomy. Methods From September 2013 to June 2014, 68 patients with breast cancer were included and divided into 2 groups, interventional group and control group. The patients in interventional group were treated with modified radical mastectomy plus Pectoralis major myocutaneous flap transfer, while the patients in control group were just received mastectomy. All the patients were followed and the upper extremity lymphedema was evaluated 0.5, 1, 3, 6, 9 months after surgery. Results According to the follow-up results, the incidence of lymphedema in interventional group was obviously lower than in control group, the difference was significant （P〈0.05）. Conclusion The Pectoralis major myocutaneous flap transfer after modified radical mastectomy can significantly reduce the chances of upper limb lymphedema, and accelerate the postoperative recovery.

关 键 词：乳腺癌 胸大肌肌瓣转移术 上肢淋巴水肿 

分 类 号：R551.2[医药卫生—血液循环系统疾病]