三层膜管壁结构的颈动脉超声仿真  

An ultrasound simulation method for carotid arteries with a wall structure of three membranes

作　　者：胡晓[1] 张榆锋[1] 高莲[1] 蔡光卉[1] 贾志国[1] 章克信[2] 邓丽[1] 

机构地区：[1]云南大学信息学院电子工程系,昆明650091 [2]昆明医学院第二附属医院,昆明650031

出　　处：《声学学报》2015年第6期871-877,共7页Acta Acustica

基　　金：国家自然科学基金(61261007;61561049);云南省自然科学基金(2013FA008)资助

摘　　要：颈动脉超声仿真有助于血管壁超声检测及信号处理方法的性能评价。提出三层膜管壁结构的颈动脉超声仿真方法。根据组织散射点分布的形状和密度与超声回声斑点分布的变化规律,对临床图像统计分析,确定对应组织散射点分布、密度及强度等特征参数,利用FIELDⅡ产生超声射频回波信号并得到B超图像。30例仿真试验结果表明,血管壁内、中、外膜及血流回声的统计分布与临床B超图像的一致;与中心频率为8 MHz的结果相比,12 MHz仿真的内、中、外膜厚度及管腔直径测量均值与预设值相等,最大相对误差分别为4.01%,1.25%,0.04%及0.15%,仿真效果更为逼真。Tile ultrasound simulation for carotid arteries is helpful to the performance assessment of vessel wall detection and signal processing method by using ultrasound techniques. A method for ultrasound simulation of carotid artery wall with a 3-membrane structure is proposed in this paper. According to the ultrasound speckle distributions varying with the shapes and densities of scatterer distributions, as well as the statistic results of the clinical images, the parameters of distributions, densities and intensities of scatterers for different kinds of tissues in the carotid artery phantoms are determined. Each region is acoustically characterized using FIELD II software to produce the radio frequency echo signals, from which ultrasound images are derived. The results based on 30 simulations show that the echo distributions of the intimae, mediae, adventitias and blood are consistent with the clinical ones. Moreover, compared with the results from the central frequency of 8 MHz, the mean measurements of thicknesses of the intima, media and adventitia membranes, as well as the lumen diameter from the simulation images based on 12 MHz are as the same as the preset ones, and the maximum relative errors are the 4.01%, 1.25%, 0.04% and 0.15%, respectively. The simulation under this condition is more realistic.

关 键 词：超声检测 仿真方法 管壁结构 颈动脉 三层膜 信号处理方法 B超图像 性能评价 

分 类 号：R543.4[医药卫生—心血管疾病] TN911.7[医药卫生—内科学]