京南保北地区毛细支气管炎流行病学及病原学调查分析  

Investigation of Pidemiology and Etiology of Bronchiolitis in the District of Baoding North and Beijing South

作　　者：侯秀玲[1] 王敬敏[1] 李桂娥 刘冬梅[1] 张趁欣 李雪萍[1] 徐林[1] 庞改玲 

机构地区：[1]河北省保定市第二中心医院,河北保定072750 [2]河北省涿州市妇幼保健院,河北涿州072750

出　　处：《儿科药学杂志》2015年第11期12-15,共4页Journal of Pediatric Pharmacy

基　　金：保定市科学研究与发展计划项目;编号14ZF109

摘　　要：目的:调查京南保北地区毛细支气管炎流行病学及病原学情况,并分析病毒感染的相关因素。方法:选取2014年1月至2015年3月我院儿科住院的京南保北地区毛细支气管炎患儿300例,对患儿临床资料进行调查,并进行病原学检测分析。结果:300例患儿均有咳嗽、喘憋等症状;血常规异常率24.3%,C-反应蛋白异常率11.3%,肝功能异常率7.0%,肾功能异常率11.3%。300例患儿中肺炎支原体Ig M阳性54例,阳性率18.0%;病毒检测阳性150例,阳性率50.0%。单因素分析显示年龄、入院前病程、C-反应蛋白、发病季节、过敏史与毛细支气管炎病毒感染有明显相关性(P<0.05)。多因素分析显示年龄、入院前病程、C-反应蛋白、发病季节为导致毛细支气管炎病毒感染的主要独立危险因素(P<0.05)。结论:京南保北地区毛细支气管炎患儿流行病学表现多样,病原学调查显示病毒和支原体感染是主要的病因,年龄、入院前病程、C-反应蛋白、发病季节可导致病毒感染的发生,要积极加强对症干预。Objective： To investigate the pidemiology and etiology of bronchiolitis in the district of Baoding North and Beijing South,and analyze factors related to viral infection. Methods： Selected 300 children with pediatric bronchiolitis from January 2014 to March2015 in our hospital in the district of Baoding North and Beijing South,then the clinical data were investigated and pathogen were detected. Results： Three hundreds children had coughing,wheezing and other symptoms. Abnormality rate of blood routine was24. 3%,C-reactive protein was 11. 3%,liver function was 7. 0%,renal function was 11. 3%. Three hundreds children with Ig M positive of Mycoplasma pneumonia was 54 cases,the positive rate was 18. 0%,150 cases of positive in virus test,the positive rate was50. 0%. Univariate analysis showed that age,disease duration before admission,C-reactive protein,the incidence of seasonal,allergies with bronchiolitis and viral infections had significant correlation（ P〈0. 05）. Multivariate analysis showed that age,disease duration before admission,C-reactive protein,mobidity season as the major independent risk factor for bronchiolitis virus infection（ P〈0. 05）.Conclusion： The epidemiology of children with bronchiolitis performance guarantee Baoding North and Beijing South diverse pathogens investigation are complicated,etiology investigation shows that the virus and mycoplasma infection were the main causes. Age,disease duration before admission,C-reactive protein and mobidity season can lead to the infection of viral,so symptomatic treatment.

关 键 词：京南保北地区 毛细支气管炎 流行病学 病原学 

分 类 号：R965.2[医药卫生—药理学]