米非司酮分别配伍依沙丫啶、米索前列醇在瘢痕子宫中期妊娠引产中的临床效果比较  

Comparison of the Curative Effect of Mifepristone Combined with Ethacridine or Misoprostol in Induced Labor in Midpregnancy of Cicatricial Uterus

作　　者：刘晓霞[1] 白云[2] 林晓娟[3] 

机构地区：[1]陕西省商洛职业技术学院附属医院妇产科 [2]陕西省商洛市中心医院产科,陕西商洛726000 [3]甘肃省妇幼保健院产前诊疗中心,甘肃兰州730050

出　　处：《昆明医科大学学报》2015年第10期55-58,共4页Journal of Kunming Medical University

基　　金：甘肃省卫生厅行业技术科研基金资助项目(2010-14)

摘　　要：目的探讨米非司酮分别配伍依沙丫啶和米索前列醇用于瘢痕子宫中期妊娠引产中的临床效果.方法将2012年5月至2014年5月陕西省商洛职业技术学院附属医院收治的瘢痕子宫中期妊娠孕妇68例分为A组和B组,每组34例.A组患者采用口服米非司酮和羊膜腔注射依沙丫啶引产,B组患者采用口服米非司酮配伍阴道放置米索前列醇引产,对2组患者的宫缩开始时间、胎盘娩出时间、产后出血量、胎盘残留量以及引产效果进行比较.结果 A组和B组的宫缩开始时间、胎盘娩出时间、产后出血量、胎盘残留量以及引产效果比较差异有统计学意义(P<0.05).结论米非司酮配伍羊膜腔注射依沙丫啶用于瘢痕子宫中期妊娠引产的临床效果优于米非司酮配伍米索前列醇的引产方法,值得临床推广.Objective To analyze the curative effect of mifepristone combined with ethacridine or misoprostol in induced labor in midpregnancy of cicatricial uterus.Methods 68 midpregnant women with cicatricial uterus in our hospital between May 2012 and May 2014 were divided into group A and group B,with 34 cases in each group.The patients in group A had oral administration of mifepristone and intra- amniotic ethacridine,while patients in group B had oral administration of mifepristone and misoprostol placed in vagina for induced labour.Uterine contraction time, delivery of placenta time, postpartum hemorrhage volume after delivery, the residue of placenta and the effect of induced labor were observed and compared.Results There were significant differences in uterine contraction time, delivery of placenta time, postpartum hemorrhage volume after delivery,the residue of placenta and the effect of induced labor between two groups（P〈0.05）.Conclusions Combination treatment with mifepristone and intra- amniotic ethacridine is more effective than oral administration of mifepristone and misoprostol placed in vagina on labour induced for patients with cicatricial uterus in midpregnancy.

关 键 词：子宫 瘢痕 中期妊娠 引产 

分 类 号：R714.12[医药卫生—妇产科学]