急性胰腺炎反应期C反应蛋白测定对病情严重程度的评估  

Assessment of the Disease Severity by C Reactive Protein in Acute Pancreatitis

作　　者：姚建辉[1] 范震[2] 

机构地区：[1]榆林市第一医院神经外科,陕西榆林719000 [2]杭州市第一人民医院消化内科,浙江杭州310006

出　　处：《昆明医科大学学报》2015年第10期107-110,共4页Journal of Kunming Medical University

基　　金：浙江省医药卫生平台骨干人才计划基金资助项目(2011RCB028)

摘　　要：目的探究血清C反应蛋白水平与急性胰腺炎患者的病情分型判定的关系,为临床诊断和治疗提供参考.方法选取2012年1月至2015年1月榆林市第一医院消化内科收治100例急性胰腺炎患者,分为轻型急性胰腺炎(MAP)组和重型急性胰腺炎(SAP)组.检测患者入院1、3、5、7 d血清CRP水平,CT检查患者胰腺,对2种分组下患者CRP水平进行比较,使用ROC曲线分析灵敏度和特异度.结果 MAP组患者、SAP组患者血清CRP水平均呈先增高后降低的趋势,MAP组患者血清CRP水平均低于SAP组患者,P<0.01;胰腺无坏死组患者血清CRP水平均低于胰腺坏死组患者,P<0.01;CRP预测SAP的灵敏度和特异度随着CRP水平的升高而提高.结论血清CRP水平可用于急性胰腺炎早期分型,有一定的临床参考意义.Objective To explore the relationship between serum C level of C- reactive protein and the classification of acute pancreatitis,and to provide reference for clinical diagnosis and treatment.Methods From January 2012 to January 2015, 100 cases of acute pancreatitis in our hospital were divided into light acute pancreatitis（MAP） group and severe acute pancreatitis（SAP） group.The levels of serum CRP were detected by1,3,5,7,and levels were compared with the patients of two groups.The sensitivity and specificity of ROC were compared with CRP curve.Results The serum levels of CRP in patients with MAP group and SAP group were increased and then decreased,and serum CRP in MAP group was lower than that in SAP group.The levels of serum CRP in pancreatic necrosis group were lower than those in pancreatic necrosis group.The sensitivity and specificity of CRP were improved with the increase of CRP levels.Conclusion Serum CRP levels can be used for early typing of acute pancreatitis,and it has a certain clinical reference value.

关 键 词：C反应蛋白 轻型急性胰腺炎 重型急性胰腺炎 胰腺坏死 

分 类 号：R676[医药卫生—外科学]