虎皮楠中1个新的环戊二烯负离子结构生物碱  

A new alkaloid with cyclopentadienyl anion moiety from Daphniphyllum oldhami

作　　者：谭承建[1,2] 邸迎彤[1] 郝小江[1] 

机构地区：[1]中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,云南昆明650201 [2]贵州民族大学化学与环境科学学院,贵州贵阳550025

出　　处：《中草药》2015年第20期2989-2991,共3页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(30830114;31100259;30800092;31360084;31360084)

摘　　要：目的研究贵州虎皮楠Daphniphyllum oldhami枝叶中生物碱成分。方法采用硅胶、Sephadex LH-20和RP18等柱色谱技术进行分离、纯化,通过MS、NMR等光谱学方法鉴定化合物的结构。结果从虎皮楠枝叶中分离得到1个虎皮楠生物碱,命名为虎皮楠素D(1)。结论化合物1为新的虎皮楠生物碱,该化合物结构中含有1个新颖的环戊二烯负离子结构单元。Objective To investigate the alkaloids of Daphniphyllum oldhami collected in Songtao of Guizhou province. Methods Column chromatographis including silica gel, Sephadex LH-20, and RP18 were used to isolate the alkaloid constituents, and their structures were elucidated by MS and NMR spectroscopic data. Results One alkaloid was obtained from D. oldhami and named as oldhamine D（1）. Conclusion Compound 1 is a new Daphniphyllum alkaloid containing a rare cyclopentadienyl anion moiety.

关 键 词：虎皮楠科 虎皮楠 生物碱 虎皮楠素D 环戊二烯负离子 

分 类 号：R284.1[医药卫生—中药学]