空腹血糖正常的门诊高血压患者代谢异常研究  

The Study of Abnormal Metabalism in Essential Hypertention out Patient with Normol Fasting Blood Glucose

作　　者：王俊利[1] 费丽萍[1] 牛青英[1] 李艳芳[1] 

机构地区：[1]长治医学院附属和济医院心内科,046011

出　　处：《长治医学院学报》2015年第5期340-343,共4页Journal of Changzhi Medical College

基　　金：长治市科技局星火科技资助项目(20104024)

摘　　要：目的:研究空腹血糖正常的门诊原发性高血压患者糖代谢异常临床特征,揭示糖耐量异常与血脂、尿酸及颈动脉粥样硬化的情况。方法:选择确诊有原发性高血压而无糖尿病的患者436例,入选患者口服葡萄糖耐量实验测定,分析年龄、性别、体重指数、血脂水平、颈动脉粥样硬化等参数与糖耐量异常的关系。结果:436例患者中检出糖耐量减低患者127例,占29.1%,糖尿病患者41例,占9.5%,糖耐量异常与性别、年龄、血尿酸水平、低密度脂蛋白、颈动脉粥样硬化呈正相关。结论:空腹血糖正常的门诊高血压患者合并糖耐量异常比例较高,常伴有血脂、尿酸及动脉粥样硬化等高危因素,应及早预防及治疗糖代谢异常及相关危险因素,从而减少糖尿病及心血管疾病发病风险。Objective：To investigate the factors that influence glucose tolerance in essential hypertention,identify the clinical characteristics of abnormal metabalism.Methods：436 outpatients with essential hypertention,with no history of diabites mellitus and normol fasting blood glucose were recruited.All eligible patients received oral glucose tolerance test. We analyzed the relationships between impaired glucose tolerance and other variables including age,gender,body mass index, blood pressure,uric acid,lipid levels,and carotid atherosclerosis plague.Results：Among 436 patients,the number of patients with impaired glucose tolerance was 127 （29.1%）,the number of newly diagnosed diabites DM was 41 （9.5%）.A positive correlation exists between glucose tolerance and other variables including age,gender,lowdensity cholesterol,uric acid and carotid atherosclerosis plague.Conclusion：High prevalence of abnormal glucose tolerance was discoved in essential hypertention patients with normol fasting blood glucose.Oral glucose tolerance test should be actively engaged in those patients to detect impaired glucose toleranc early.And it is helpful to postpone progression of diabites and reduce risk of cardelvassculer and cerebrovassculer disease.

关 键 词：高血压 糖耐量 尿酸 血脂 颈动脉粥样硬化 

分 类 号：R544.1[医药卫生—心血管疾病]