老年2型糖尿病患者血清铁蛋白水平与胰岛素抵抗的相关性分析  

Association between serum ferritin and insulin resistance in elderly patients with type 2 diabetes mellitus

作　　者：庄文翔[1] 倪黎刚[2] 

机构地区：[1]江苏省省级机关医院老年科,江苏省南京市210024 [2]江苏省省级机关医院检验科,江苏省南京市210024

出　　处：《实用老年医学》2015年第10期831-833,共3页Practical Geriatrics

摘　　要：目的分析老年2型糖尿病患者血清铁蛋白(SF)水平与胰岛素抵抗(IR)的相关性。方法选择40例老年2型糖尿病患者为糖尿病(T2DM)组,40例健康老人为对照组。所有病人均测定体质量指数(BMI)、腹围、血压、血清铁蛋白(SF)、糖化血红蛋白、空腹血糖、血脂、空腹胰岛素等,计算胰岛素抵抗指数(HOMA-IR),比较分析SF与各项指标的相关性。结果糖尿病组血清SF水平明显高于对照组。SF水平与BMI、腹围、血压、空腹血糖、糖化血红蛋白、HOMA-IR成正相关。结论老年T2DM患者SF水平明显升高,SF与糖代谢相关。SF可能是IR的预测指标。Objective To analyze the association between serum ferritin（ SF） and insulin resistance（ IR） in elderly patients with type 2 diabetes mellitus. Methods Forty elderly patients with type 2 diabetes mellitus were selected as DM group and 40 healthy subjects selected as control group. Body mass index（ BMI）,wasist circumstance（ WC）,systolic blood pressure（ SBP）,diastolic blood pressure（ DBP）,SF,Hb A1 c,fasting plasma glucose（ FPG）,lipids,FINS,HOMA-IR were detected and compared between two groups. Results The level of SF was significantly higher in DM group than that in the control group. The level of SF was significantly positively correlated with BMI,WC,SBP,DBP,FPG,Hb A1 c,HOMAIR. Conclusions The level of SF is significantly higher in elderly patients with type 2 diabetes mellitus,which implicates some association with glucose metabolism and insulin resistance. Ferritin may be a predictor of IR.

关 键 词：老年人 2型糖尿病 血清铁蛋白 胰岛素抵抗 

分 类 号：R587.1[医药卫生—内分泌]