老年人睡眠障碍与退行性心脏瓣膜病关系的临床研究  

Relationship of sleep disorders with degenerative heart valvular disease in the elderly

作　　者：刘春君[1] 徐杰 朱爱华[3] 戴煌[3] 沈翔[3] 

机构地区：[1]中国人民解放军第三二二医院门诊部,山西省大同市037600 [2]海军青岛辛家庄干休所门诊部,山东省青岛市226071 [3]中国人民解放军第三五九医院老干科,江苏省镇江市212001

出　　处：《实用老年医学》2015年第10期844-846,共3页Practical Geriatrics

基　　金：南京军区"十一五"计划课题(06MA70)

摘　　要：目的研究老年人睡眠障碍与退行性心脏瓣膜病(DHVD)的关系。方法选择有睡眠障碍的老年人276例作为睡眠障碍组,男234例,女32例;无睡眠障碍的277例老年人作为对照组,男235例,女32例。采用匹兹堡睡眠质量指数(PSQI)量表进行睡眠障碍评估并比较,同时用超声诊断仪进行心脏检查,观察并比较2组相关指标。结果睡眠障碍组和对照组基本情况比较无统计学差异(P>0.05)。2组PQSI量表相关参数评分比较,睡眠障碍组各项参数均高于对照组,差异有统计学意义(P<0.05或P<0.01)。睡眠障碍组右室流出道(RVOT)、主动脉根部内径(AO)、左房内径(LA)、室间隔厚度(IVST)、左室舒张末期内径(LVDd)和右室舒张末期内径(RVDd)与对照组比较均有统计学差异(P<0.05或P<0.01)。2组心脏主动脉瓣和二尖瓣增厚、反射增强、钙化、关闭不全及狭窄的发生率均有统计学差异(P<0.05或P<0.01)。结论老年人睡眠障碍可能促发DHVD发生和发展。Objective To investigate the relationship of sleep disorders with degenerative heart valvular disease（ DHVD） in the elderly. Methods 276 cases with sleep disorder were selected as sleep disorder group（ 234 male and 32females）. 277 cases without sleep disorder were enrolled as control group（ 235 male and 32 females）. The two groups were matched in gender,age and basic diseases（ P 0. 05）. Pittsburgh sleep quality index（ PSQI） scale was evaluated and the heart function was detected by using ultrasonography in two groups. Results There was no significant difference in basic information betweent two groups. The score of PSQI in sleep disorder group was significantly higher than that in control group（ P 0. 05 or P 0. 01）. There were significant differences in RVOT,AO,LA,IVST,LVDd and RVDd betweent two groups（ P 0. 05 or P 0. 01）. The incidence rates of thickening,reflecting enhanced,calcification,regurgitation,and stenosis of aortic valve and mitral valve were significantly higher in sleep disorder group than those in control group（ P 0. 05 or P 0. 01）. Conclusions Elderly sleep disorders may trigger DHVD development and progression.

关 键 词：老年人 睡眠障碍 退行性心脏瓣膜病 心脏彩超 

分 类 号：R542.5[医药卫生—心血管疾病]