血清降钙素原在老年支气管肺炎中的诊疗价值  

Value of serum procalcitonin in the diagnosis and treatment of senile bronchial pneumonia in the elderly patients

作　　者：章邱东[1] 

机构地区：[1]阜阳市人民医院老年科

出　　处：《实用老年医学》2015年第10期867-869,共3页Practical Geriatrics

摘　　要：目的通过测定支气管肺炎患者血中降钙素原(PCT)的含量变化,探讨其在老年支气管肺炎患者中的诊疗价值。方法选择安徽阜阳市人民医院老年科2013年1月至2014年10月住院老年细菌性支气管肺炎患者35例为肺炎组。分别于治疗前、抗生素应用2 d、5 d后行PCT、白细胞(WBC)计数的检测。并选择健康人群(符合非感染人群)25例作为对照组。结果 (1)肺炎组治疗前PCT、WBC计数与对照组比较均有升高,差异有统计学意义(P<0.05)。(2)肺炎组有效治疗后PCT水平有显著的动态下降,治疗前后比较差异有统计学意义(P<0.05)。(3)肺炎组治疗前、后WBC计数差异无统计学意义(P>0.05)。(4)肺炎组患者PCT水平皆大于临界值(0.05 ng/ml),敏感率达100%,WBC计数有27例大于临界值(10×109/L),敏感率达77%。(5)35例中有4例演变为重症肺炎(死亡2例),其PCT水平入院后明显增高且高居不下,而WBC计数无上述特点。结论老年肺炎患者血清PCT检测对其诊断、疗效评价及预后判断有重要意义,且敏感性优于WBC计数。Objective To study the value of serum procalcitonin（ PCT） in the diagnosis and treatment of senile bronchial pneumonia in the elderly patients. Methods Thirty-five elderly patients with bacterial bronchopneumonia in the department of geriatrics of Fuyang People＇s Hospital from January 2013 to October 2014 were enrolled in this study. The levels of PCT and WBC count were measured before the treatment,two days or five days after using antibiotics. Twenty-five healthy people were enrolled as control group. Results（ 1） The levels of PCT and WBC in the pneumonia group before treatment were significantly higher than those in control group（ P 0. 05）.（ 2） After treatment,the level of PCT was significantly decreased in the pneumonia group（ P 0. 05）.（ 3） After treatment,the changes of the level of WBC count was not significant in the pneumonia group（ P 0. 05）.（ 4） The level of PCT of the selected 35 patients in the pneumonia group was higher than the critical value（ 0. 05 ng / ml） with a sensitive rate of 100%,meanwhile the level of WBC count of 27 patients was over the critical value（ 10 × 109/ L） with a sensitive rate of 77%.（ 5） Of the 35 patients,4 suffered from severe pneumonia（ and 2 die）,and the level of PCT remained at a high level,while WBC counts did not show such characteristics. Conclusions Serum PCT is of great importance in the diagnosis,efficacy evaluation and prognosis for bronchial pneumonia with better susceptibility than WBC count.

关 键 词：支气管肺炎 老年人 降钙素原 

分 类 号：R563.12[医药卫生—呼吸系统]