原发性颅内淋巴瘤46例临床分析  

Clinical analysis of 46 cases of primary intracranial lymphoma

作　　者：柯炎斌[1] 陆永建[1] 方泽鲁[1] 曹国彬[1] 

机构地区：[1]广州医科大学附属第二医院神经外科,广州510260

出　　处：《广东医学院学报》2015年第3期364-366,共3页Journal of Guangdong Medical College

摘　　要：目的总结原发性颅内淋巴瘤的治疗方法及其疗效。方法回顾性分析46例原发性颅内淋巴瘤患者临床资料。结果肿瘤全切除7例,近全切除15例,部分切除11例,立体定向活检13例。42例行术后联合放化疗,3例行单纯化疗。单发病灶患者平均生存期为(34.3±5.6)个月,多发病灶患者均已死亡,平均生存期为(16.2±3.7)个月。结论早期联合放化疗可延长原发性颅内淋巴瘤患者生存期和改善生存质量。Objective To summarize the therapeutic methods and efficacy of primary intracranial lymphoma. Methods Clinical data of 46 cases of primary intracranial lymphoma were retrospectively analyzed. Results Total, subtotal and partial tumor resection, and stereotactic biopsy were performed on 7, 15, 11 and 13 cases, respectively. Three patients received simple chemotherapy, while 42 subjects accepted combined radio-chemotherapy. The mean survival time was （34.3± 5.6） months for patients with single lesion and （16.2±3.7） months for multiple lesions. All patients with multiple lesions have died. Conclusion The early combined radio-chemotherapy can prolong the survival time and improve the quality of life in patients with primary intracranial lymphoma.

关 键 词：淋巴瘤 脑肿瘤 

分 类 号：R551.2[医药卫生—血液循环系统疾病]