蒽环类药物化疗患者早期心电图和超声心动图的变化  

Effect of anthracyclines on early changes of electrocardiogram and echocardiogram

作　　者：黄邹琴[1] 付珊珊[2] 李涛[1] 刘观成[1] 罗良平[3] 

机构地区：[1]广州医科大学附属肿瘤医院,广州510095 [2]南方医科大学珠江医院,广州510282 [3]暨南大学第一临床医学院,广州510630

出　　处：《广东医学院学报》2015年第4期434-435,共2页Journal of Guangdong Medical College

摘　　要：目的了解蒽环类药物对肿瘤患者早期心电图和超声心动图的影响。方法 80例肿瘤患者在蒽环类药物化疗前、化疗后2周作心电图和超声心动图检查,比较QRS波、T波电压及左室射血分数变化。结果与化疗前比较,化疗2周后患者心电图QRS波和T波电压明显降低(P<0.01),但左室射血分数差异无统计学意义(P>0.05)。结论心电图检查可发现蒽环类药物所致早期QRS波和T波改变。Objective To investigate the effect of anthracyclines on early changes of electrocardiogram and echocardiogram in cancer patients. Methods Eighty cancer patients underwent electrocardiogram and echocardiogram before and 2 weeks after anthracycline chemotherapy. QRS and T-wave voltages and left ventricular ejection fraction（LVEF） were compared. ResultsQRS and T-wave voltages were lower after chemotherapy than those before chemotherapy（P〈0.01）, but LVEF was similar between before and after chemotherapy（P〈0.05）. Conclusion Electrocardiography can reveal the early changes of QRS and T waves caused by antharcyclines.

关 键 词：蒽环类药物 心电图 超声心动图 

分 类 号：R540.41[医药卫生—心血管疾病]