大剂量沐舒坦联合纤支镜治疗胸外科术后重症肺炎的疗效观察  

Clinical efficacy of high-dose mucosolvan and bronchofiberscopy in severe pneumonia after thoracic surgery

作　　者：黄河[1] 麦晓勤 孙小聪[1] 胡桂芳[1] 

机构地区：[1]广东医学院附属医院,广东湛江524001

出　　处：《广东医学院学报》2015年第4期456-458,共3页Journal of Guangdong Medical College

摘　　要：目的观察大剂量沐舒坦联合纤支镜治疗胸外科术后重症肺炎的疗效。方法 60例胸外科术后重症肺炎患者随机分成治疗组和对照组。对照组在基础治疗上加常规剂量沐舒坦治疗,而治疗组在基础治疗上加大剂量沐舒坦联合纤支镜治疗,比较两组患者的疗效。结果与对照组比较,治疗组Pa O2/Fi O2升高更显著(P<0.01),白细胞、降钙素原降低更明显(P<0.01),机械通气时间、ICU住院时间明显缩短(P<0.01),但两组患者的治愈情况差异无统计学意义(P>0.05)。结论大剂量沐舒坦联合纤支镜治疗胸外科术后重症肺炎可改善氧合、减轻炎症反应、减少机械通气时间和ICU住院时间。Objective To observe the clinical efficacy of high-dose mucosolvan and bronchofiberscopy in severe pneumonia after thoracic surgery. Methods Sixty cases of severe pneumonia after thoracic surgery were randomly divided into 2 groups. Control group received basic therapy and conventional dose mucosolvan, while treatment group accepted basic therapy and highdose mucosolvan. The clinical efficacy was compared between 2 groups. Results Compared with control group, Pa O2/Fi O2 was increased（P〈0.01）, levels of leukocytes and procalcitonin were decreased（P〈0.01）, and mechanical ventilation time and length of stay in ICU were shorten（P〈0.01） in treatment group. However, the cure rate was similar between 2 groups（P〈0.05）. Conclusion Combined use of high-dose mucosolvan and bronchofiberscopy can improve oxygenation, reduce inflammation, and shorten mechanical ventilation time and length of stay in ICU for severe pneumonia after thoracic surgery.

关 键 词：沐舒坦 纤支镜 重症肺炎 

分 类 号：R563.1[医药卫生—呼吸系统]