通天口服液制备工艺改进  

Improvement of preparing technique for Tongtian oral liquid

作　　者：苏红专[1] 谢彦兵[1] 李海兵[1] 艾凌艳[1] 

机构地区：[1]解放军第一八四医院,鹰潭335000

出　　处：《国际药学研究杂志》2015年第5期658-661,共4页Journal of International Pharmaceutical Research

摘　　要：目的利用新型过滤装置改进通天口服液的过滤及蒸馏液添加工艺。方法以涤纶滤布替换传统过滤工艺中的滤纸,放置于板框过滤机上,并添加滑石粉做助滤剂。蒸馏液不加吐温80增溶而直接加入到通天口服液清膏中,充分搅拌,加10%Na OH调p H值至4.5~6.5,加水至1200 L,再用上述过滤装置滤过,即得。结果与传统工艺所得制剂相比,改进工艺所得制剂澄清,质量合格,口感更佳。结论改进工艺符合通天口服液的制备要求,具备工艺简单稳定,产品口感好,减轻劳动强度且生产成本低的优点,有着广阔的应用前景。Objective To improve the filtering technique and the addition methods of distillate for Tongtian oral liquid with a new type of filtering equipment. Methods The filter paper in the current filtering process was replaced with a combination of terylene filter cloth and pulvis talci. Distillate was added into the runny paste of preparation directly without using the solubilizer of Tween-80. Then the admixture was agitated sufficiently. After that,10% Na OH was used to adjust the p H to 4.5-6.5,and the solution was added to 1200 L by water. At last,a clear preparation was obtained by using the above filtering equipment. Results Compared with the product made by the current method,the improved preparation was qualified and tasty. Conclusion The improved method is feasible,simple and economical. The product is tasty.

关 键 词：通天口服液 涤纶滤布 过滤 口感 工艺 

分 类 号：R283[医药卫生—中药学]