丙泊酚预防MECT术后不良反应效果观察  

Effect of propofol for prevention of side effects in patients after MECT

作　　者：王晓敏 姜海涛 沈曙光 贾玉萍 

机构地区：[1]上海交通大学医学院附属精神卫生中心,上海市200030

出　　处：《精神医学杂志》2015年第5期334-335,共2页Journal of Psychiatry

基　　金：国家临床重点专科-上海市精神卫生中心(编号:2011-873)

摘　　要：目的观察依托咪酯诱导MECT脑电发作结束后静推丙泊酚对预防术后不良反应的疗效。方法选取首次MECT治疗患者120例,随机分为丙泊酚诱导组(Ⅰ组)、依托咪酯诱导组(Ⅱ组)和依托咪酯诱导脑电发作结束后静推丙泊酚组(Ⅲ组)各40例,观察患者脑电发作持续时间、术后24 h内出现的急性谵妄、头痛及低热情况。结果Ⅱ、Ⅲ组MECT脑电发作持续时间较Ⅰ组延长(P<0.05);急性谵妄、头痛、低热及总不良反应发生率I组少于Ⅱ组(P<0.05)。结论 MECT脑电发作结束后静推丙泊酚对预防术后不良反应具有明显的疗效。Objective To explore the effects of propofol for prevention of side effects in patients after MECT.Methods A total of 120 patients receiving MECT for the first time were randomly divided into group Ⅰ（40 cases） induced with propofol, groupⅡ（40 cases） induced with etomidate and groupⅢ（40 cases） injected with propofol following etomidate-induced MECT. They were assessed with the durations of cecebral attack,occurrence of acute delirium, headache and low fever within 24 hours after MECT.Results The durations of cerebral attack in group II and group Ⅲ were significantly longer than that in group Ⅰ（P〈0.05）.The incidence rates of acute delirium, headache, low fever and total side effects in group I were significantly lower than those in group Ⅱ（P 〈0.05）.Conclusion It’s effective for propofol injection following etomidate-induced MECT to prevent the side effects in patients after MECT.

关 键 词：无抽搐电休克治疗 依托咪酯 丙泊酚 急性谵妄 头痛 低热 

分 类 号：R614[医药卫生—麻醉学]