Fibroscan对乙型肝炎病毒携带者纤维化的诊断  

Fibroscan in the diagnosis of liver fibrosis to hepatitis B virus carriers

作　　者：苏冬娜[1] 吴诗品[1] 汤小俐 

机构地区：[1]暨南大学附属第二医院深圳市人民医院感染内科,广东深圳518020 [2]深圳市蛇口人民医院放射科,广东深圳518067

出　　处：《暨南大学学报（自然科学与医学版）》2015年第5期435-438,共4页Journal of Jinan University(Natural Science & Medicine Edition)

基　　金：深圳市科技计划项目(201103321)

摘　　要：目的:探讨3种乙型肝炎病毒携带者肝纤维化程度的差异,为评估预后提供参考.方法:将114例乙肝病毒携带者分组为:乙肝抗原(HBe Ag)阳性HBV DNA阳性携带者(A组)、HBe Ag阴性HBV DNA阴性携带者(B组)、HBe Ag阴性HBV DNA阳性携带者(C组).使用fibroscan对乙型肝炎病毒携带者进行肝脏硬度值(LSM)检测,评估3组肝脏硬度值的差异.结果:A组与B组,B组与C组的肝脏硬度值有显著性差异,A组与C组的肝脏硬度值无显著性差异.结论:说明HBV DNA阳性的携带者无论HBe Ag是否阳性其肝脏硬度值均比HBV DNA阴性的携带者增高.Aim：To investigate the difference of liver fibrosis degree in three groups of hepatitis B vi-rus carriers.Methods：114 hepatitis B virus carriers were randomly divided into three groups：A group was positive for HBeAg and positive for HBV DNA;B group was negative for HBeAg and positive for HBV DNA;C group was negative for HBeAg and negative for HBV DNA.Three groups hepatitis B virus carri-ers were examined liver stiffness measurement （LSM）by Fibroscan.Results：There were significant difference in liver stiffness measurements between A group and B group,also between B group and C group,but no significant difference between A group and C group.Conclusion：Liver stiffness measure-ments of hepatitis B virus carriers with positive for HBV DNA were markedly higher than those with nega-tive for HBV DNA,whether HBeAg was positive or not.

关 键 词：慢性乙型肝炎病毒 携带者 肝脏硬度值 

分 类 号：R512.6[医药卫生—内科学]