不同剂量芬太尼复合异丙酚用于无痛人工流产术的麻醉效果观察  

Clinical observation on anestheitic effects of propofol with different dosage of fentanyl for artificial abortion

作　　者：聂津[1] 解素勇 王奕芳[1] 邵伟[1] 

机构地区：[1]河北省唐县人民医院,河北唐县072350

出　　处：《医学研究与教育》2015年第4期17-19,43,共4页Medical Research and Education

摘　　要：目的观察不同剂量芬太尼复合异丙酚用于无痛人工流产术的麻醉效果和安全性。方法将120例ASAⅠ～Ⅱ级人工流产患者随机分为两组，即芬太尼2．0μg／kg组（A组，n=60）和芬太尼1．0μg／ks组（B组，n=60）。观察并记录两组患者麻醉前、手术中、手术结束时的血压（MAP）、心率（HR）、呼吸频率（RR）、血氧饱和度（SpO2）变化，术毕苏醒时间以及异丙酚用量、术后腹痛情况。结果A组麻醉镇痛效果优于B组，异丙酚用药量明显减少，术后苏醒快，不良反应减少及术后腹痛满意率增高（P〈0．05）。结论适量增大芬太尼剂量应用于无痛人流术麻醉镇痛效果更佳，术后患者舒适度2．0μg／ks优于1．0μg／ks。Objective To observe the anesthetic effects and satety of the fentanyl and propofol in painless artificial abortion. Methods 120 cases with ASA Ⅰ～Ⅱ artificial abortion were randomly divided into two groups. Group A （60 cases） was anesthetized with fentanyl 1.0μg/kg and group B （60 cases） was anesthetized with fentanyl 2.0 μg/kg. The changes of blood pressure, heart rate, breath rate and oxygen saturation were observed during the anesthesia. The dose of propofol, the time for recovery and leaving hospital and the incidence of abdominal pain after operation were recorded. Results Effective analgesia were induced in 2 groups. The results indicated that the effects in group A were better than that in group B, dosage of propofol decreased obviously, with quicker postoperative recovery, less adverse reactions and higher satisfaction （P〈0.05）. There was statistical significance between the 2 groups. Conclusion Suitable increasing the dose of fentanyl in painless abortion have some advantages of safety and effects, the results of 2.0 μg/kg is superior to that of 1.0 μg/kg.

关 键 词：芬太尼 异丙酚 人工流产 麻醉效果 

分 类 号：R614[医药卫生—麻醉学]