滋肾活血法治疗血管性痴呆肾阴虚血瘀证的临床研究  

Clinical Observation of Nourishing Kidney and Promoting Blood Circulation Therapy for Treatment of Vascular Dementia

作　　者：伍大华[1] 姚婷[1] 蒋军林[1] 龙华君[1] 邓谦[1] 唐沛兰[1] 周慎[1] 

机构地区：[1]湖南省中医药研究院附属医院,长沙410006

出　　处：《中西医结合心脑血管病杂志》2015年第12期1372-1374,共3页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：湖南省科技厅项目(No.2013TZ2015)

摘　　要：目的观察滋肾活血法治疗血管性痴呆(VD)肾阴虚血瘀证的临床疗效。方法按纳入标准选择50例VD肾阴虚血瘀证患者,根据随机、对照原则分为治疗组和对照组各25例,治疗组予滋肾活血法治疗,对照组予奥拉西坦胶囊治疗。治疗前后进行简易精神状态量表(MMSE)、日常生活活动量表(ADL)、中医证候、美国国立卫生院卒中量表(NIHSS)等评分。结果最终纳入统计的病例为48例(治疗组与对照组各24例),脱落2例。治疗3个月后,治疗组疾病总有效率优于对照组(87.50%比70.83%,P<0.05)。治疗组治疗后MMSE积分、ADL积分、中医证候积分、NIHSS积分,较治疗前明显改善,差异有统计学意义(P<0.05或P<0.01),且治疗组后MMSE积分、ADL积分、中医证候改善程度优于对照组(P<0.05)。结论滋肾活血法为治疗VD肾阴虚血瘀证的有效治法,疗效优于奥拉西坦胶囊。Objective To observe the clinical effect of nourishing kidney and promoting blood circulation（NKPBC）therapy for treatment of vascular dementia（VD）with the syndrome of insufficiency of kidney-yin and blood stasis（IKYBS）in TCM by the of.Methods Fifty patients with VD were randomized into two groups：Treatment group（n=25）treated by NKPBC and control group（n=25）treated with Oxiracetam capsule.The scores of Mini Mental State Examination（MMSE）,Activity of Daily Living（ADL）,NIHSS and Chinese medicine syndrome were observed before and after treatment.Results Forty-eight cases were finally included in the statistics,2 cases were fallen off.After three months,the total effective rate was 87.50%in treatment group and 70.83%in control group（P0.05）.We analyzed the TCM syndrome integral,MMSE,ADL and NIHSS,it suggested that the treat group was better than the control group,there were significant differences（P〈0.05 or P〈0.01）.Conclusion The therapy of NKPBC had a certain effect for VD with the syndrome of IKYBS.

关 键 词：血管性痴呆 滋肾活血法 肾阴虚血瘀证 

分 类 号：R277.7[医药卫生—中医学]