痰热清注射液联合硝酸甘油雾化吸入对慢性肺源性心脏病患者细胞免疫功能的影响  

Effects of Tanreqing Injection and Nebulized Nitroglycerin Inhalation on Cellular Immune Function in Patients with Chronic Pulmonary Heart Disease

作　　者：王庆蕊[1] 

机构地区：[1]河北省唐山市第八医院,河北唐山063020

出　　处：《中西医结合心脑血管病杂志》2015年第13期1520-1522,共3页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

摘　　要：目的评价痰热清注射液联合硝酸甘油雾化吸收对慢性肺源性心脏病患者细胞免疫功能的影响。方法将80例慢性肺源性心脏病患者随机分为两组,每组40例。对照组给予常规治疗;观察组在对照组治疗方式基础上,加用痰热清注射液联合雾化吸入硝酸甘油治疗。结果观察组总有效率90.0%,高于对照组总有效率70.0%,差异具有统计学意义(P<0.05)。治疗后,观察组患者二氧化碳分压(PaCO2)、肺动脉压力低于对照组,而观察组患者氧分压(PaO2)高于对照组,差异具有统计学意义(P<0.01)。治疗后,观察组患者CD8+T高于对照组,而观察组患者CD3+T、CD4+T及CD4+/CD8+T低于对照组,差异具有统计学意义(P<0.05)。结论痰热清注射液联合硝酸甘油治疗慢性肺源性心脏病疗效显著,能够有效降低患者肺动脉压力,并改善细胞免疫功能。Objective To study the effect of Tanreqing injection（TRQI）and nebulized nitroglycerin （Neb NTG）inhalation on cel ular immune function in patients with chronic pulmonary heart disease （CPHD）.Methods Eighty patients with CPHD were randomly di-vided into two groups：The control group（n=40）treated with routine treatment ,and the treatment group（n=40）treated with TRQI plus Neb NTG inhalation in the basis of routine treatment.Results The total clinical effective rate was 90.0% in treatment group, which was higher than that in control group（70.0%,P〈0.05）.After treatment,the levels of arterial partial pressure of carbon dioxide （PaCO2 ）,pulmonary arterial pressure in treatment group were lower than that in control group,while the levels of arterial partial pres-sure of oxygen（PaO2 ）were higher than that in control group（P〈0.01）.After treatment,CD8＋ T cel in treatment group were higher than that in control group,while CD3＋T cel ,CD4＋ T cel and CD4＋/CD8＋T cel were lower than those in the control group（P〈0.05）.Conclusion TRQI and Neb NTG inhalation can effectively reduce the pulmonary artery pressure and improve the cel ular im-mune function in patients with CPHD.

关 键 词：慢性肺源性心脏病 痰热清注射液 硝酸甘油 免疫功能 

分 类 号：R541.5[医药卫生—心血管疾病]