高渗脱水药物治疗创伤性脑水肿的疗效分析  

Efficacy of Hypertonic Dehydration Therapy in the Treatment of Traumatic Brain Edema

作　　者：王红旭[1] 

机构地区：[1]河南省平顶山市第一人民医院神经内科,467000

出　　处：《中国卫生标准管理》2015年第28期130-131,共2页China Health Standard Management

摘　　要：目的探讨创伤性脑水肿采用高渗脱水药物治疗临床效果。方法选取60例创伤性脑水肿,随机分组,以20%甘露醇降颅压治疗(对照组,n=30)与高渗脱水药物降颅压治疗(观察组,n=30)效果展开对比。结果观察组颅内压最大降幅、起效时间分别为(9.1±2.8)mm Hg和(25±8.2)min,对照组分别为(9.4±3.2)mm Hg和(23.2±10.3)min,对比均无差异(P>0.05)。观察组药物作用持续时间(264±64)min,对照组(220±52)min,组间比较有统计学差异(P<0.05)。两组行CT复查,中间移位均>0.5 cm,可采取手术方案治疗。结论针对创伤性脑水肿,采用高渗脱水药物治疗,可延长药物持续作用时间,为患者手术的开展提供了良好条件。Objective To discuss the efficacy of hypertonic dehydration therapy in the treatment of traumatic brain edema. Methods Sixty patients with traumatic brain edema,randomized,20% mannitol on intracranial pressure lowering treatment（control group,n=30）and hypertonic dehydration intracranial pressure lowering medication treatment（study group,n=30）expand contrast effect. Results The biggest drop in intracranial pressure observation group,the onset time was（9.1±2.8）mm Hg and（25±8.2）min,respectively,in the control group（9.4±3.2）mm Hg and（23.2±10.3）min,there was no significant difference in comparison（P〉0.05）. Duration of drug action in the observation group（264±64）min,the control group（220±52）min,a relatively significant difference（P〈0.05）between groups. Two row CT scans,middle shifts 〉0.5cm,can be taken to surgery regimen. Conclusion For traumatic brain edema,hypertonic dehydration medication,drugs prolong duration of action time,carry out surgery for patients provided good conditions.

关 键 词：高渗脱水药物 创伤性脑水肿 疗效观察 

分 类 号：R971[医药卫生—药品]