三脉紫菀挥发油化学成分的GC-MS分析  

GC-MS Analysis of Chemical Components of Volatile Oil from Aster ageratoides

作　　者：元文君 任刚[1] 李文艳[2] 李敏[1] 朱继孝[1] 

机构地区：[1]江西中医药大学中药资源与民族药研究中心,南昌330004 [2]江西中医药大学护理学院,南昌330004

出　　处：《中国实验方剂学杂志》2015年第21期47-50,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家自然科学基金项目(81160509;81360475);江西省青年科学家培养计划项目(20142BCB23024);江西省教育厅科学技术研究项目(GJJ14614);江西省卫生厅中医药科研计划项目(2013A029)

摘　　要：目的:研究三脉紫菀挥发油的化学组成及相对含量。方法:采用水蒸气蒸馏法提取三脉紫菀叶中的挥发油,并通过气相色谱-质谱(GC-MS)联用仪对其化学成分进行分析和鉴定,用色谱峰面积归一化法计算各组分相对百分含量。结果:从三脉紫菀挥发油中共分离出124个组分,鉴定了其中72个化合物,占总量的67.52%,主要成分为石竹烯氧化物(caryophyllene oxide,18.38%),环氧化蛇麻烯II(12-oxabicyclo[9.1.0]dodeca-3,7-diene,1,5,5,8-tetramethyl-,[1R-(1R,3E,7E,11R)]-,8.01%),石竹烯(caryophyllene,3.57%),十六烷酸(n-hexadecanoic acid,4.59%),蛇麻烯(humulene,3.16%),植酮(2-pentadecanone,6,10,14-trimethyl,2.51%),柏木脑(cedrol,2.35%),β-榄香烯(1-ethenyl-1-methyl-2,4-bis(1-methylethenyl)-,[1S-(1(,2β,4β)]-cyclohexane,2.28%),2,5-二甲氧黄樟油精(apiol,1.85%),匙叶桉油烯醇[(-)-spathulenol,1.32%]等。结论:三脉紫菀挥发油中主要含萜类、酯类、醇类、醛类、烃类等多种化学成分;分析结果可为三脉紫菀挥发油的质量控制和进一步研究提供科学依据。Objective： To analyze the chemical components of the volatile oil from Aster ageratoides and determine their contents. Method： The volatile oil was extracted from A. ageratoides by steam distillation. Its chemical components were analyzed and identified by GC-MS, and the relative percentage content of each component was calculated by area normalization method. Result： One hundred and twenty-four compounds were isolated from the volatile oil of A. ageratoides and 72 of them were identified,accounting for 67. 52% of volatile oil. The major components were caryophyllene oxide（ 18. 38%）,12-oxabicyclo [9. 1. 0] dodeca-3,7-diene,1,5,5,8-tetramethyl-, [1R-（ 1R,3E,7E,11R） ]-（ 8. 01%）,caryophyllene（ 3. 57%）,n-hexadecanoic acid（ 4. 59%）,humulene（ 3. 16%）,2-pentadecanone,6,10,14-trimethyl（ 2. 51%）,cedrol（ 2. 35%）,cyclohexane,1-ethenyl-1-methyl-2,4-bis（ 1-methylethenyl）-,[1S-（ 1（,2β,4β） ]-cyclohexane（ 2. 28%）,apiol（ 1. 85%）,（-）-spathulenol（ 1. 32%）. Conclusion： The volatile oil from A. ageratoides is mainly consisted of terpenoids,esters,alcohols,aldehydes,hydrocarbons and other chemical components. The analytic results can provided scientific basis for quality control and further exploitation of A. ageratoides.

关 键 词：三脉紫菀 挥发油 水蒸气蒸馏 气相-质谱联用 

分 类 号：R284.1[医药卫生—中药学]