宣痹汤加减治疗痛风性关节炎临床疗效的Meta分析  

Meta-analysis of Curative Effect of Xuanbi Tang in Treating Gouty Arthritis

作　　者：平凡[1] 李成荫[2] 朱丰林 王红艳[1] 晏婷婷[1] 闵楷家 汪悦[1] 

机构地区：[1]南京中医药大学,南京210023 [2]重庆市中医院,重庆400021

出　　处：《中国实验方剂学杂志》2015年第21期193-196,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家中医药管理局重点学科(中医痹证学)开放基金项目(BBXK2013101);江苏省高校"青蓝工程"优秀青年骨干教师培养项目(2012)

摘　　要：目的:对宣痹汤加减方治疗痛风性关节炎(gouty arthritis,GA)的疗效进行Meta分析及安全性评价。方法:通过检索CNKI,VIP,万方数据库,查找国内关于宣痹汤加减方治疗GA的随机对照试验(RCT),检索日期自建库至2015年6月。纳入文献进行Jadad评分,运用Cochrane协作网提供的Rev Man 5.3软件进行有效率统计分析。统计药物不良反应。结果:共纳入符合标准文献11篇,Jadad评分高质量文献1篇,低质量文献10篇,Meta分析结果显示,有效率比较,治疗组优于对照组,结果具有统计学意义(P<0.01),漏斗图提示不对称。不良反应比较,实验组不良反应2例,对照组不良反应8例。结论:宣痹汤联合西药或单用均能改善痛风性关节炎,具有较好临床疗效,且不良反应少。Objective： To systematically assess the clinical efficacy and safety of Xuanbi Tang in treating gouty arthritis. Method： Retrieving relative randomized controlled trial studies applying Xuanbi Tang in treating gout arthritis published before July 2015 from several online databases of CNKI,VIP and Wanfang.Literature were retrieved and extracted,and evaluated with Jadad score by two reviewers respectively. Software Review Manager 5. 3 was used for statistics. Analyzing drug reactions. Result： A total of 11 randomized control trials studies were included. One gets high score,the others get low score. The clinical efficacy of the experimental group is better than the control group＇s（ P〈0. 01）. Funnel figure is asymmetric. Furthermore,less adverse reactions were found in experimental group. Conclusion： The Xuanbi Tang has a good clinical curative effect and less adverse reactions.

关 键 词：痛风性关节炎 宣痹汤 META分析 随机对照试验 

分 类 号：R195.1[医药卫生—卫生统计学]