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机构地区:[1]山东中医药大学,济南250014
出 处:《中国实验方剂学杂志》2015年第21期197-201,共5页Chinese Journal of Experimental Traditional Medical Formulae
基 金:山东中医药大学附属医院院级课题项目(20130906)
摘 要:目的:基于中医传承辅助系统(V2.0)软件,探讨《中华医典》中收载的所有治疗中风的古方用药规律,包括药性规律、常用药物、药对及新方组合等,以期为中风病的治疗提供思路和方法。方法:收集并筛选《中华医典》光盘中历代治疗中风的内服方剂,录入中医传承辅助系统软件,运用软件的数据挖掘方法,寻找高频药物、药类、药对等,探讨治疗中风病药物配伍规律,以方测证,从中总结古方治疗中风之病因病机。结果:根据方剂纳入与排除标准,共筛选出符合方剂617首,涉及中药320味,数据统计结果显示,在治疗中风的常用药物中,以风药为主,其中排名前10的高频药物为防风、川芎、甘草、肉桂、当归、天麻、附子、麻黄、天南星、羌活;药对以川芎与防风最为常见;关联规则显示"它药->防风"的关联规律,并得出13首治疗中风的新方。结论:根据分析得出古代医家在治疗中风时,重视对风药的配伍使用,并以辨证论治为指导,辅以开窍、活血、化痰之法,可以为临床治疗中风提供参考。Objective: Using Traditional Chinese Medicine Inheritance Support System( TCMISS)( V2. 0) software to analyze the composing principles of the prescriptions for stroke collected in the disk of The Chinese Medical,including drug law,commonly used drugs,couplet medicines and new drug combination and so on,in order to provide new ideas and methods for treatment of stroke. Method: Collect and sift the oral prescriptions used for stroke in the disk of The Chinese Medical,then enter into the TCMISS,by using the excavation method from the integration of the software,through looking for the high frequency of drugs,drug properties,and couplet medicines in order to investigate stroke medicine compatibility rule,which can summarize etiology and pathogenesis of the ancient treatment of stroke. Result: According to the inclusion and exclusion criteria,we get a total of 617 prescriptions,involving 320 kinds of traditional Chinese medicine. The statistical results of the data shows us that wind medicine is most frequently used and the top ten high frequency drugs are Radix Sileris,Ligusticum Wallichii,Liquorice,Cinnamon,Chinese Angelica,Gastrodia Elata,Monkshood,Herba Ephedrae,Rhizoma Arisaematis,Notopterygium Incisum. The most frequently used medicine match are Ligusticum Wallichii and Radix Sileris. In the last,13 new prescriptions are discovered from the study.Conclusion: According to the analysis of prescriptions,we reach a conclusion that ancient physicians attach great importance to the use of wind medicine when they treat stroke. Furthermore,under the guidance of syndrome differentiation,treatment is supplemented by inducing resuscitation,invigorate the circulation of blood and reduce phlegm,which can provide a reference for clinical treatment.
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