乌桕叶片中抑螺提取物的主要化学成分分析  

Analysis on main chemical components in oncomelania-inhibited extracts from leaf of Sapium sebiferum

作　　者：杨永峰[1] 孙启祥[2] 

机构地区：[1]国家林业局调查规划设计院,北京100714 [2]中国林业科学研究院林业研究所,北京100091

出　　处：《植物资源与环境学报》2015年第3期115-117,共3页Journal of Plant Resources and Environment

基　　金："十二五"国家科技支撑计划项目(2011BAD38B07)

摘　　要：血吸虫病是严重危害人类生命健康的寄生虫病,中国是血吸虫病流行最严重的国家之一,虽然近期得到了有效控制,但局部地区并不乐观。主要原因之一是无法有效控制血吸虫病中间宿主钉螺的传播。Oncomelania-inhibited component in petroleum ether extracts from leaf of Sapium sebiferum （Linn.） Roxb. was researched by column separation technology and GC-MS method, and compound separated from leaf was identified by NIST 107 and Wiley 6.0. The results show that relative peak areas of 3,7,11,15-tetramethyl-2-hexadeeen-l-ol, hexadecanoic acid, 9,12,15-oetadecadienoic acid methyl ester, 1,2-benzenedicarboxylic acid bis （2-ethylhexyl） ester and 8,11,14- eicosatrienoic acid are larger, and suggesting that they are the main oncomelania-inhibited compounds. In which, hexadecanoic acid may be one of active materials inhibiting oncomelania from S. sebiferum. This result has an important value to extension of biological measure controlling schistosomiasis.

关 键 词：乌桕 钉螺 抑螺成分 GC-MS 

分 类 号：Q946[生物学—植物学] Q949.99