心脏手术术后谵妄的研究进展  

Progress of research on the deliriums after cardiac surgery

作　　者：刘卫卫[1] 薄禄龙[1] 朱文忠[1] 

机构地区：[1]第二军医大学附属长海医院麻醉科,上海200433

出　　处：《国际麻醉学与复苏杂志》2015年第11期994-996,1022,共4页International Journal of Anesthesiology and Resuscitation

基　　金：上海青年医师培养资助计划（20141093）

摘　　要：背景心脏手术术后谵妄可增加患者并发症的发生率，并与远期预后相关。目的以心脏手术患者术后谵妄为切入点。从其定义、病因、诊断、防治等方面予以综述。内容心脏手术术后谵妄发生率较高，其发生与患者预后不良相关，并可增加中风、认知功能减退的风险，与远期病死率相关。谵妄的病因学及病理生理机制未完全明确。推荐非药物策略预防谵妄，抗精神病药物在其防治上尚存争议。趋向临床医师应充分认识到心脏手术术后谵妄的危害性，积极探索并寻找防治谵妄的新方法。Background Delirium is associated with both short and long-term morbidity and mortality in surgical patients. Objective To review the definition, etiology, diagnosis, prevention and treatment strategies associated with delirium after cardiac surgery. Content The incidence of delirium after cardiac surgery is estimated at a high level. Delirium after cardiac surgery is associated with poor prognosis, relating to long-term mortality, which contributes to higher risk of stroke, and substantial cognitive. Effectiveness of prophylactic antipsychotics to reduce the risk of delirium is controversial. The evidence that antipsychotics in cardiac surgery patients reduce duration of delirium or improve long-term outcomes following delirium is not scientifically justified. Trend Clinicians in the intensive care unit（ICU ） should recognize the impact of delirium to predict long-term outcomes for patients. Further research will be designated to determine interventions that will be effective in preventing and treating delirium for cardiac surgical patients.

关 键 词：麻醉 心脏手术 谵妄 术后认知功能障碍 氟哌啶醇 

分 类 号：R614[医药卫生—麻醉学]