温州地区儿童幽门螺杆菌感染流行病学调查分析  

Epidemiological investigation of helicobacter pylori infection among children in Wenzhou

作　　者：王敏[1] 王林霞[1] 汤鲁明[1] 严纯雪[1] 潘国权[1] 

机构地区：[1]温州医科大学附属第二医院,浙江温州325027

出　　处：《中国公共卫生管理》2015年第5期688-690,共3页Chinese Journal of Public Health Management

基　　金：浙江省医药卫生科技计划项目(2013RCA039)

摘　　要：目的调查研究温州地区儿童幽门螺杆菌（Helicobacter pylori,H.p）感染的流行病学特征及影响因素。方法采用分层抽样方法抽取2010年4月-2015年2月在本院儿科就诊并检测血清中幽门螺杆菌抗体（HP-Ig G）的儿童4 520例,分析H.p感染率及感染特征,并抽取450例儿童对其家长进行问卷调查。结果 4 520名儿童中,HP-Ig G阳性者2 118例,感染率为46.9%;1~3岁、4~7岁和8~14岁HP-Ig G阳性率分别为38.1%、44.9%、61.8%;对H.p感染的危险因素进行分析,单因素分析显示,家庭人口数、经济收入、人均居住面积、共用餐具、公用牙刷口杯、父母患胃病、父母卫生习惯等是H.p感染发生的危险因素;进一步对多因素回归分析显示,经济收入、共用餐具、公用牙刷口杯、父母患胃病、父母卫生习惯是儿童H.p感染发生的独立危险因素。结论温州地区儿童H.p感染率较高,感染率随着儿童年龄增加而增加;家庭经济收入、共用餐具、公用牙刷口杯、父母患胃病、父母卫生习惯与儿童H.p感染密切相关,应该加强对危险因素的控制进而控制H.p感染。Objective To investigate the epidemiological characteristics and risk factors of Helicobacter pylori（Hp）infection in children in Wenzhou. Methods 4520 children accepted serum HP-Ig G detection in the hospital during April2010 to February 2015 were selected by stratified sampling method,Hp infection and characteristics of infection were analyzed,450 children＇ parents were selected for questionnaire,include： personal information,food hygiene habits,socioeconomic status,stomach history in family members. The risk factors for Hp infection in children were analyzed according to the survey results. Results 2118 cases were detected with Hp-Ig G positive in 4520 children,the infection rate was 46.9%; Hp-Ig G positive rate was 38.1%,44.9%,61.8% in 1-3 years old,4-7 years old and 8-14 years old,respectively; risk factors for Hp infection were analyzed,univariate analysis showed that the number of family,income,per capita living space,sharing utensils,utility toothbrush cup,parents suffering from stomach problems,parental health habits are risk factors for Hp infection,and further multivariate regression analysis showed that income,sharing utensils,utility toothbrush cup,parents suffering from stomach problems,parental health habits is an independent risk factor for childhood Hp infection occurred. Conclusion Children Hp infection rate was a little higher in Wenzhou region,the infection rate increased with increasing age of the child; family income,sharing utensils,utility toothbrush cup,parents suffering from stomach problems,parental health habits closely associated with Hp infection in children,risk factors should be strengthened to control Hp infection.

关 键 词：幽门螺杆菌 流行病学 危险因素 单因素分析 

分 类 号：R183.4[医药卫生—流行病学] R181.81[医药卫生—公共卫生与预防医学]