颅脑损伤并发2型糖尿病患者胰岛素泵的临床应用  

Clinical application of insulin pump in craniocerebral injury patients combined with type 2 diabetes mellitus

作　　者：杨茜[1] 严臻泉[1] 柳晓锋[1] 张金峰[1] 门焕丽 侯永革[1] 

机构地区：[1]河北省石家庄市第一医院神经科重症监护室,河北石家庄050011

出　　处：《河北医科大学学报》2015年第10期1139-1141,1145,共4页Journal of Hebei Medical University

摘　　要：目的探讨颅脑损伤并发2型糖尿病患者胰岛素泵临床应用的必要性。方法将颅脑损伤并发2型糖尿病患者83例随机分为胰岛素泵(continuous subcutaneousinsulin infusion,CSII)组43例,普通胰岛素多次皮下注射(multiple subcutaneous insulin injection,MSII)40例,观察2组治疗后血糖达标时间、每日胰岛素用量、低血糖发生率、格拉斯哥昏迷量表(Glasgow Coma Scale,GCS)评分、住院时间、住院费用。结果 CSII组血糖达标时间短于MSII组,每日胰岛素用量少于MSII组,低血糖发生率低于MSII组,预后GCS>8分的比例高于MSII组,住院时间和住院费用少于MSII组(P<0.05或<0.01)。结论胰岛素泵治疗颅脑损伤并发2型糖尿病患者,血糖达标快速平稳,可明显改善患者的预后。Objective To explore the clinical application of insulin pump in craniocerebral injury combined patients with type 2diabetes mellitus（T2DM）.Methods Eighty-three patients of craniocerebral injury combined with T2 DM were randomly divided into the application of insulin pump control blood sugar group（CSII group,n=43）,application of common multiple subcutaneous insulin injection（MSII group,n=40）.Blood glucose control time,insulin daily dosage,hypoglycemia incidence,Glasgow Coma Scale（GCS）score,the average length of hospital stay,hospital expenses in two groups were observed after treatment.Results The blood glucose control tome of CSII group was shorter than that of MSII group,daily insulin dosage of CSII group was less than that of MSII group,CSII group had lower incidence of hypoglycemia than MSII group,the prognosis of GCS 〉8scores was higher than in MSII group,the proportion of the length of hospital stay and hospital costs were less than those of MSII group（P〈0.05or0.01）.Conclusion Blood glucose control target is fast and smooth as insulin pump was used to treat craniocerebral injury patients combined with T2 DM,it significantly improves the prognosis of patients.

关 键 词：颅脑损伤 糖尿病 2型 胰岛素输注系统 

分 类 号：R651[医药卫生—外科学] R587.1[医药卫生—临床医学]