东莞地区健康人群空腹血糖、餐后2h血糖与年龄的相关性分析  

Correlation analysis of age and fasting blood glucose, 2 h postprandial blood glucose of healthy population in Dongguan area

作　　者：荣秀花[1] 

机构地区：[1]中山大学附属东华医院内分泌科,广东东莞523110

出　　处：《中国医药导报》2015年第32期108-111,共4页China Medical Herald

基　　金：广东省东莞市科技计划医疗卫生类科研一般项目(201310515000153)

摘　　要：目的研究东莞地区健康人群空腹血糖、餐后2 h血糖与年龄的相关性。方法选择2013年5月~2014年7月东莞地区的健康人群作为研究对象,随机抽取≤35岁、〉35~45岁、〉45~55岁、〉55~60岁、〉60~65岁、〉65~70岁、〉70~75岁、〉75~80岁、〉80岁人群各150例,检测入组者的空腹血糖水平、餐后2 h血糖水平、胰岛素水平、糖化血红蛋白水平。结果≤35岁、〉35~45岁、〉45~55岁、〉55~60岁、〉60~65岁人群的空腹血糖水平、餐后血糖水平、糖化血红蛋白水平低于〉65~70岁、〉70~75岁、〉75~80岁、〉80岁人群（P〈0.05）;其胰岛素水平高于〉65~70岁、〉70~75岁、〉75~80岁、〉80岁人群（P〈0.05）;其空腹血糖受损例数、餐后血糖受损例数少于〉65~70岁、〉70~75岁、〉75~80岁、〉80岁人群（P〈0.05）。结论随着年龄增长,血糖代谢发生异常,表现为血糖水平和糖化血红蛋白水平升高、胰岛素水平降低、胰岛素抵抗加重;定期体检有助于早期发现糖尿病。Objective To study correlation between age and fasting blood glucose, 2 h postprandial blood glucose of healthy population in Dongguan area. Methods Healthy population from May 2013 to July 2014 in Dongguan area were enrolled in this study, ≤ 35 years, 〉35-45 years,〉 45-55 years, 〉55-60 years, 〉60-65 years,〉 65-70 years, 〉70-75 years, 〉75-80 years, 〉80 years healthy population were randomly collected, with 150 cases in each group. Fasting blood glucose level, 2 h postprandial blood glucose level, insulin level, glycosylated hemoglobin level, insulin resistance index and insulin sensitive index were detected. Results Fasting blood glucose level and 2 h postprandial blood glucose level, glycosylated hemoglobin level of ≤ 35 years, 〉35-45 years, 〉45-55 years, 〉55-60 years, 〉60-65 years groups were lower than those of 〉65-70 years, 〉70-75 years, 〉75-80 years, 〉80 years（P〈0.05）; Their insulin levels was higher than those of 〉65-70 years,〉 70-75 years,〉 75-80 years, 〉80 years（P〈0.05）; Their fasting blood glucose and postprandial impaired blood glucose cases were less than those of 〉65-70 years, 〉70-75 years,〉 75-80 years, 〉80 years groups（P〈0.05）.Conclusion Glucose metabolism become abnormal with age, manifesting as blood glucose and glycosylated hemcglobin levels increasing, insulin level decreasing and insulin resistance aggravating; Regular physical examination is helpful to diagnose diabetes.

关 键 词：糖尿病 血糖 糖化血红蛋白 胰岛素抵抗 

分 类 号：R587[医药卫生—内分泌]