LEEP治疗宫颈上皮内瘤变219例临床分析  

A Clinical Analysis of LEEP Surgery in 219 CIN Cases

作　　者：李俊强[1] 刘绪义 陈晨[1] 李春梅[1] 

机构地区：[1]四川大学华西第二医院,四川成都610041 [2]四川省眉山市妇幼保健院,四川眉山620000

出　　处：《实用妇产科杂志》2015年第11期874-877,共4页Journal of Practical Obstetrics and Gynecology

基　　金：四川省学术和技术带头人培养重点资金项目(编号:2012DPY0027)

摘　　要：目的：探讨宫颈环形电切术（LEEP）治疗宫颈上皮内瘤变（CIN）的应用效果及分析阴道镜下活检诊断CIN的价值。方法：回顾分析四川大学华西第二医院2012年1～12月收治的219例CIN患者行LEEP治疗的疗效，及阴道镜下活检与最终病理诊断的符合情况。结果：LEEP对于CIN的总治愈率为97．67％（210例），残留率2．33％（5例）；发现4例早期浸润癌；术后回访无明显并发症；术后妊娠35例；最终病理诊断与术前病检符合者200例（91．32％），病理级别升高19例（8．68％）。结论：早期积极的LEEP治疗CIN是预防宫颈癌发生的有效措施，特别适用于治疗有生育要求的CIN患者；LEEP术不仅能有效治疗CIN，还可避免阴道镜下活检对CIN的诊断不足。Objective：To explore the value of loop electrosurgical excision procedure（LEEP）in treatment of cervical intraepithelial neoplasia（CIN） treatment and the value of colposcopic biopsy in diagnosis of CIN. Methods： It was a retrospective analysis of 219 CIN cases,who were diagnosed by colposcopic biopsy and treated by LEEP in our hospital from January 2012 to December 2012. Results：The total cure rate of LEEP for CIN was 97. 67% （210 cases）. The residual rate was 2.33% （5 cases）. 4 cases of minimally invasive cancer were found after LEEP. 35 cases achieved pregnancy after surgery. The coincidence rate between colposcopic biopsy and LEEP pathology was 91.32% （200 cases）. Post-LEEP pathology increased in 19 cases （8. 68% ）, in comparison with colposcopic biopsy. Conclusions：LEEP surgery is an effective treatment to prevent occurrence of cervical cancer, especially for CIN patients with birth demand. LEEP, can also effectively avoid the inadequacy of colposcopic biopsy in diagnosis of CIN.

关 键 词：宫颈上皮内瘤变 宫颈环形电切术 疗效 诊断 

分 类 号：R711.74[医药卫生—妇产科学]