甾族糖苷生物碱研究进展  

Research Advances on Steroidal Glycoalkaloids

作　　者：许蕙金兰 王翠翠[1] 傅达奇[1] 

机构地区：[1]中国农业大学食品科学与营养工程学院,北京100083

出　　处：《生物技术通报》2015年第10期24-30,共7页Biotechnology Bulletin

基　　金：国家"863"计划资助项目(2012AA101702)

摘　　要：甾族糖苷生物碱是茄科植物中广泛存在的一种物质,存在于植物的叶子、根、花、果实和块茎中,具有多种生物活性,如抗癌、抗真菌、抗病毒、抗氧化及抗炎等功能。关于植物中糖苷生物碱的分布、含量、生物活性及合成代谢途径的研究一直是本领域的研究热点。糖苷生物碱生物合成分子机理的研究将为优良品种的培育提供理论依据。对甾族糖苷生物碱的结构、生物活性及其生物合成途径进行了综述。Steroidal glycoalkaloid is a substance wildly existing in solanaceae plants, i.e., in plant＇s leaves, roots, flowers, fruits and tubers, and it possesses broad biological activities, such as anticancer, antifungal, antiviral, antioxidant, and anti-inflammatory functions etc. Researches on the distribution, content, biological activities and synthesis pathways of steroidal glycoalkaloids have always been hot topics in this field. The research on the molecular mechanisms of steroidal glycoalkaloids＇ biosynthesis will provide theoretical basis for breeding fine varieties. In this paper, the structure, biological activities and biosynthetic pathways of steroidal glycoalkaloids are reviewed.

关 键 词：甾族糖苷生物碱 生物活性 合成途径 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]