PFOS对再生东亚三角涡虫抗氧化酶活性的影响  

Effects of PFOS on the Activities of Antioxidant Enzyme in Regenerated Dugesia japonica

作　　者：苗自利 袁佐清[1] 

机构地区：[1]山东理工大学生命科学学院,淄博255049

出　　处：《生物技术通报》2015年第10期211-215,共5页Biotechnology Bulletin

基　　金：国家自然科学基金资助项目(31100377);山东省自然科学基金资助项目(ZR2011CQ018)

摘　　要：为了探究全氟辛烷磺酸(Perfluorooctane sulfonate,PFOS)对再生涡虫抗氧化酶活性的影响,以再生中的涡虫作为实验材料,采用酶活性的测定的方法来探究PFOS对再生中东亚三角涡虫中抗氧化酶活性的影响。结果表明,PFOS刺激涡虫产生应激反应。在再生早期,PFOS胁迫会造成涡虫的氧化损伤和脂质的过氧化,并表现出随着PFOS浓度的升高,涡虫氧化损伤程度加剧的趋势;再生5 d时,机体产生抗氧化的反应来消除体内的氧自由基;在再生的后期,由于涡虫对药物的耐受作用,涡虫的抗氧化反应不显著。Perfluorooctane sulfonate（PFOS）, a persistent organic pollutant, has been a typical predominant perfluorinat ed chemicals（PFCs）in the environment. In this study, we used regenerated planarians（Dugesia japonica）to evaluate the toxicological effects of PFOS on the activities of antioxidant enzyme. The results indicated that PFOS stimulated planarians to generate the stress responses. In the early stage of regeneration, PFOS stress caused oxidative damage and lipid perox ide of planarians, with the concentration of PFOS increasing, oxidative damage degree of pla narian intensified;at the 5th day of regeneration, the body produced oxidation reaction to eliminate oxygen free radicals;in the late stage of regeneration, the oxidation reaction of planarian was no longer significant because of drug tolerance.

关 键 词：PFOS 东亚三角涡虫 再生 抗氧化酶活性 

分 类 号：X503.22[环境科学与工程—环境工程]