冠状动脉病变程度与窦性心率震荡的相关性研究  

Study on Correlations Between the Degree of Coronary Artery Lesion and Heart Rate Turbulence

作　　者：王卓亚[1] 杨发满[1] 刘冀[1] 杨青岩[1] 李军[1] 李晓平[1] 李蓉[1] 

机构地区：[1]青海大学附属医院老年二科,810001

出　　处：《青海医药杂志》2015年第9期5-9,共5页Qinghai Medical Journal

摘　　要：目的：研究冠状动脉病变程度与窦性心率震荡（HRT）的相关性。方法：选择西宁地区110例完成冠状动脉造影的患者,根据冠状动脉造影结果分为病变组（83例）,对照组（27例）,病变组亚组分为轻度狭窄组（28例）、中度狭窄组（31例）、重度狭窄组（24例）。冠状动脉造影前（1-3）天行24小时动态心电图检查,计算心率震荡参数震荡初始（TO）,震荡斜率（TS）,比较病变组和对照组及病变组各组间HRT的变化。结果：1病变组较对照组TO明显升高（P〈0.01）,TS明显降低（P〈0.01）,差异有统计学意义;2病变组亚组分析显示随冠脉狭窄程度的加重,TO逐渐升高,在轻度、中度、重度狭窄组之间差异具有统计学意义（P〈0.05）;TS逐渐降低,在轻度、中度、重度狭窄组之间差异具有统计学意义（P〈0.05）。相关分析显示TO与冠脉狭窄程度呈高度正相关（rs=0.87）;TS与冠脉狭窄程度呈高度负相关（rs=-0.84）。结论：冠状动脉病变程度与HRT密切相关,HRT可作为评价冠脉病变患者狭窄程度的指标之一,因此对冠心病患者行HRT测定将有助于对患者病情的了解,有助于临床指导患者进一步检查治疗,改善预后,降低猝死率。Objective：To analysis the correlation between the coronary artery lesion and heart rate turbulence （HRT）. Methods：Coronary angiography was completed in patients suspected coronary artery disease . 110 patients were divided to two groups：coronary artery lesion group（83cases） and control group（27eases）. And the patients in disease group were divided into low- grade narrow group（28 cases） ,moderate narrow group（31 cases）and the se- rious narrow group （24 cases）. （1 - 3 ）days before coronary angiography, 24 hours dynamic electrocardiogram wasused to collect HRT parameter：TO and TS. Comparing the differences of HRT among them . Results ： （!）Compared with the control group ,the value of TO was significantly higher in disease group（P 〈 0.01 ）while the value of TS was significantly lower in disease group（P 〈0.01 ） ;（2）The tery lesion become more serious, the value of TO become moderate narrow group and the serious narrow group. The subgroup analysis in the disease group, the coronary ar- higher especially among the low -grade narrow group, difference among them has statistical significance （P 〈 0. 01 ）. Also the difference of the value of TS among the low - grade narrow group,moderate narrow group and the serious narrow group has statistical significance（ P 〈0. 01 ）. TO is positively correlated with the narrow level of the coronary artery （ rs = 0. 87 ） while TS is negatively correlated with the narrow level of the coronary artery （ rs = -0. 84）. Conlusion：There is correlation between the extent of coronary disease and the HRT parameters. HRT can be a useful marker to evaluate the severity of the narrow of the coronary artery .

关 键 词：窦性心率震荡 冠状动脉病变 动态心电图 冠状动脉造影 

分 类 号：R541.4[医药卫生—心血管疾病]