冠状动脉支架5毫米以外近端与远端再狭窄的比较研究  

Effect of stents' patency on artherosclerotic progression of the adjacent more than 5mm reference segments

作　　者：李颖娜[1] 吴芳[1] 田树平[2] 宋翔[1] 具海月[1] 杨立[1] 

机构地区：[1]解放军总医院-放射科,100853 [2]中国人民解放军海军总医院放射科

出　　处：《心肺血管病杂志》2015年第10期745-747,751,共4页Journal of Cardiovascular and Pulmonary Diseases

基　　金：国家自然科学基金(81371547)

摘　　要：目的:探究支架通畅情况对支架近远端5mm以外的节段血管节段的动脉粥样硬化进展的影响。方法:回顾性分析支架置入术后行冠状动脉血管造影(coronary angiography,CAG)的患者78例,分为支架无狭窄组与支架再狭窄组,收集两组支架两端5mm以外血管节段的粥样硬化进展情况。结果:支架无狭窄组,支架近端5mm以外血管节段的Gensini积分小于远端血管节段[53.2(27.6,75.1)vs.70.1(32.1,83.1)分,P<0.01];而在支架再狭窄组,两者无明显差异[54.7(23.1,74.2)vs.59.3(24.6,80.1)分,P>0.05]。同时支架无狭窄组,支架近远端5mm以外血管节段粥样硬化发生率高于支架再狭窄组(50.6%vs.23.1%;P<0.05)。结论:支架远端5mm以外血管节段粥样硬化较易出现于无狭窄时,且远端狭窄程度多大于其近端。Objective：Stents has influence on vessels at distal or proximal adjacent reference segments （≤5mm）. The aim of this study is to investigate the potential impact of stent＇ s patency on segments at distal or proximal sites more than 5mm. Methods： Retrospectively review 78 patients who were performed coronary angi- ography （CAG） after stent implantation. The data describing the vessels＇ stenosis are obtained at baseline and follow up, and all the patients are divided into non-instent stenosis group and stent restenosis group. Results： In the non-instent stenosis group, the Gensini＇s score at the distal segment was greater than the proximal seg- ment[ 53.2 （27.6,75.1）vs. 70. 1 （32. 1,83. 1 ） , P 〈 0. 01 ] ; although no significance difference is seen in the stent restenosis group [ 54. 7 （23.1,74. 2） vs. 59.3 （24. 6,80. 1 ）, P 〉 0.05 ]. The incidence of atherosclerosis of vessel segements （ 〉 5mm） in the non-instent stenosis group is higher than the other group（50. 6% vs. 23.1% ; P 〈 0.05 ）. Conclusion： Atheroscierosis tends to happen more when the stent is non-instent stennsis, and the percent of stenosis at the distal segment is higher than that at the proximal one.

关 键 词：支架再狭窄 支架两端血管 无支架血管 粥样硬化 

分 类 号：R54[医药卫生—心血管疾病]