Synthesis of N-benzothiazol-2-yl-amides by Pd-catalyzed C(sp^2)–H functionalization  

作　　者：Jun-Ke Wang Ying-Xiao Zong Xi-Cun Wang Yu-Lai Hu Guo-Ren Yue 

机构地区：[1]Key Laboratory of Hexi Corridor Resources Utilization of Gansu Universities, College of Chemistry and Chemical Engineering, Hexi University [2]Gansu Key Laboratory of Polymer Materials, College of Chemistry and Chemical Engineering, Northwest Normal University [3]Gansu Engineering Laboratory of Applied Mycology, Hexi University

出　　处：《Chinese Chemical Letters》2015年第11期1376-1380,共5页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(Nos.21462016,21262010);Natural Science Foundation of Gansu Province and the Advanced Research Fund of Jinchuan Group Co.,Ltd

摘　　要：A catalytic synthesis of N-benzothiazol-2-yl-amides from 1-acyl-B-（phenyl）thioureas was achieved in the presence of a palladium catalyst through the C（sp2）-H functionalization/C-S bond formation, This synthetic methodology can produce various N-benzothiazol-2-yl-amides in high yields with good functional group tolerance.A catalytic synthesis of N-benzothiazol-2-yl-amides from 1-acyl-B-（phenyl）thioureas was achieved in the presence of a palladium catalyst through the C（sp2）-H functionalization/C-S bond formation, This synthetic methodology can produce various N-benzothiazol-2-yl-amides in high yields with good functional group tolerance.

关 键 词：BenzothiazolePal-catalyzed1 -Acyl-3 -phenylthioureaC-H functionalizationL-Proline 

分 类 号：O621.3[理学—有机化学]