2型糖尿病住院患者甲状腺功能指标分布特点  

Distribution characteristics of thyroid hormones levels in admitted patients with type 2 diabetes mellitus

作　　者：王燕[1] 王莹[1] 毕文凯[1] 路坤娜[1] 宋晓[1] 张新焕[1] 

机构地区：[1]泰山医学院附属医院内分泌科,山东泰安271000

出　　处：《泰山医学院学报》2015年第8期875-877,共3页Journal of Taishan Medical College

摘　　要：目的调查2型糖尿病(type 2 diabetes mellitus,T2DM)住院患者甲状腺功能指标分布特点并分析其可能临床意义。方法选择2014年1月至2015年6月在泰山医学院附属医院内分泌科住院的193例2型糖尿病患者为糖尿病组,选择同期101例健康查体人员为对照组,均抽取空腹血,比较两组间促甲状腺激素(Thyroid-stimulating hormone,TSH)、游离三碘甲状腺原氨酸(Free triiodothyronine,FT3)、游离甲状腺激素(Free thyroxin FT4)、糖化血红蛋白(Hemoglobin A1c,Hb A1c)、总胆固醇(Total cholesterol,TC)、甘油三酯(Triglycerides,TG)、高密度脂蛋白(High-density lipoprotein cholesterol,HDL-C)、低密度脂蛋白(Low-density lipoprotein cholesterol,LDL-C)。结果糖尿病组FT3、FT4低于对照组(P<0.05),TC、TG、LDL-c较对照组升高(P<0.05);糖尿病组中男性TSH较女性降低(P<0.05),糖尿病A组(即Hb A1c≤7%组)TSH较糖尿病B组(即Hb A1c>7%组)降低(P<0.05)。结论住院2型糖尿病患者常伴有甲状腺激素异常,临床上需进一步重视2型糖尿病患者甲状腺功能筛查,及时进行干预。Objective ： To investigate distribution characteristics of thyroid hormones levels in admitted patients with type2 diabetes mellitus and analyze its possible clinical significance. Methods ：193 admitted patients with T2DM （DM group）and 101 healthy patients （control group） from January 2014 to June 2015 in Department of Endocrinology from AffiliatedHospital of Taishan Medical University were enrolled; All clinical parameters include thyroid - stimulating hormone（ TSH ） , Free triiodothyronine （ FI3 ） , Free thyroxin （ FT4 ） , Hemoglobin A1 c （ HbA1 e ） , Total cholesterol （ TC ） , Triglycer-ides （ TG）, High - density lipoprotein cholesterol （ HDL - C ） , Low - density lipoprotein cholesterol （ LDL - C） were com-pared between two group. Results FT3, FT4 in DM group is lower than those in control group（ P 〈 0.05 ） ,TC,TG,LDL- ein DM group is higher than those in control group（ P 〈 0.05 ） ;TSH of male is lower than TSH of female in DM group（ P 〈0.05 ） ,TSH in DM group with HbAlc below 7% is lower than those in DM group with HbAle higher than 7% （P 〈0.05 ）.Conclusion Patients with T2DM always accompanied by thyroid dysfunction, we should pay more attention to investigate thethyroid function of patients with T2DM.

关 键 词：2型糖尿病 甲状腺功能 

分 类 号：R587.1[医药卫生—内分泌]