微创内固定对股骨远端骨折患者炎症反应和关节功能的影响  

Minimally Invasive Internal Fixation on Inflammatory Stress Reaction and Joint Function of Patients with Distal Femur Fracture

作　　者：陈焜[1] 杨立东[1] 韩正峰[1] 白秋铁[1] 王国栋[2] 

机构地区：[1]北京市垂杨柳医院,北京100022 [2]首都医科大学附属北京同仁医院,北京100730

出　　处：《现代生物医学进展》2015年第32期6312-6314,6388,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金项目(81071515)

摘　　要：目的:探讨微创内固定系统治疗对股骨远端骨折患者炎症应激反应和关节功能的影响。方法:收集2011年5月-2014年5月期间于我院接受治疗的股骨远端骨折患者100例,根据手术方式不同,将患者分为观察组和对照组,每组各50例。观察组患者给予微创内固定系统治疗,而对照组患者给予股骨髁钢板内固定治疗。比较两组患者术后炎症应激反应和关节功能状况。结果:观察组患者手术时间、手术中出血量、影像学检查患者愈合时间、完全负重下地活动时间均优于对照组,两组比较差异具有统计学意义(P<0.05);术后6个月及12个月,观察组患者HSS评分与Harris评分均明显高于对照组,两组比较差异具有统计学意义(P<0.05);手术后观察组患者的IL-1、ACTH、E、NE水平均明显优于对照组,比较差异具有统计学意义(P<0.05)。结论:微创内固定系统治疗可有效减小手术创伤以及软组织的损伤,有效缓解患者炎症应激反应,进一步促进手术后骨折的愈合,改善患者关节功能,值得临床推广。Objective： To investigate the effects of minimally invasive internal fixation system on inflammatory stress reaction and joint function of patients with distal femur fracture. Methods： 100 cases of patients undergoing the treatment of distal femoral fractures in May 2011 to 2014 in our hospital were selected and according to the different methods, the patients were divided into two groups with 50 cases in each group. The patients in the observation group were treated with minimally invasive internal fixation system, while the patients in the control group were treated with femoral condyle plate fixation. Then the inflammatory reaction and joint function after treatment of the two groups were compared. Results： The operation time, amount of bleeding in operation, imaging examination in patients with healing time, activity time with complete loads in the observation group were superior than the control group, with significant differences between the two groups （P〈0.05）; after the operation for 6 months and 12 months, the HSS and Harris scores in the observation group were significantly higher than those of the control group, with significant differences between the two groups （P〈0.05）; after the operation, the IL-1, ACTHE and NE levels in the observation group were significantly better than those of the control group, with statistically significant differences （P〈0.05）. Conclusion： Minimally invasive internal fixation system can effectively reduce the operation wound and soft tissue injury, which is worthy of clinical promotion.

关 键 词：微创内固定系统 股骨远端骨折 关节功能 

分 类 号：R683[医药卫生—骨科学]