糖尿病肺损害的研究进展  

Research Progress of Diabetes and Lung Impairment

作　　者：田湘萍[1] 孙海涛[1] 许建民[1] 王慎田[1] 

机构地区：[1]潍坊医学院附属益都中心医院内分泌科,山东青州262500

出　　处：《医学与哲学（B）》2015年第10期72-74,共3页Medicine & Philosophy(B)

摘　　要：糖尿病可导致全身多系统损害,近年来,糖尿病肺损害逐渐引起重视,大量研究证实肺可能是糖尿病的靶器官之一。糖尿病肺损害组织形态学表现主要是肺基底膜和细胞外基质的改变以及超微结构的变化。肺功能的改变主要是弥散功能障碍。关于糖尿病肺损害的机制尚不清楚,可能与糖基化产物、氧化应激及炎性因子等因素有关。糖尿病肺损害目前无统一的诊断标准,在临床上最常用的诊断方法就是无创肺功能检查。糖尿病肺损害的防治,需积极控制血糖,建议早期应用胰岛素,部分降糖药有改善肺功能的作用。Hyperglycemia can result in systematic and organic damage in patients with diabetes. In recent years , animal and clinical research show that diabetes can induce lung impairment, so lung may be one target of diabetes. Diabetes result in the structural and functional impairment of lung. The mechanism of the diabetic lung is unknown, may relate to the AGES, oxidation and inflammation factors. There is no consistent diagnostic criteria of diabetic lung impairment at present, but the most commonly diagnostic method in clinical practice is no invasive pulmonary function test. The treatment methods of diabetic lung impairment include good blood glucose control, especially early application of insulin.

关 键 词：糖尿病 糖尿病肺 肺损害 

分 类 号：R587.1[医药卫生—内分泌]