地佐辛致呼吸抑制与过度镇静  

Respiratory depression and excessive sedation due to dezocine

作　　者：廖完敏[1] 艾玲[1] 张咸伟[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院麻醉科,武汉430030

出　　处：《药物不良反应杂志》2015年第5期391-392,共2页Adverse Drug Reactions Journal

摘　　要：1例49岁女性患者全身麻醉下行腹腔镜子宫肌瘤剔除＋宫腔镜检术，麻醉苏醒后因疼痛静脉注射地佐辛2.5 mg。约20 s后患者进入睡眠状态，压眼眶反应迟钝，脉搏血氧饱和度0.80，口唇发绀，呼吸频率7次/min，呼吸幅度变浅。立即给予鼻导管吸氧，1 min后患者脉搏血氧饱和恢复至1.00，呼吸频率恢复至16次/min，患者逐渐清醒。A 49 year-old female underwent laparoscopic uterine myoma plus hysteroscopy operation under general anesthesia. She received an intravenous injection of dezocine 2.5 mg because of pain after anesthesia recovery. About 20 seconds later she fell asleep. She developed orbit-pressing reflex slowing, cyanosis of lips, and reduced amplitude of respiration. Her pulse oxygen saturation was 0.80, breathing rate was 7 beats/min. The patient received nasal catheter oxygen immediately. Her pulse oxygen saturation returned to 1.00, breathing rate increased to 16/min one minute later, and regained consciousness gradually.

关 键 词：地佐辛 呼吸功能不全 深度镇静 

分 类 号：R614[医药卫生—麻醉学] R737.33[医药卫生—外科学]