脉搏指示连续心输出量监测下人参四逆汤早期目标治疗感染性休克  

Research on ginseng-Sini early goal directed treats septic shock under PICCO

作　　者：马建强[1,2] 吴疆[2] 

机构地区：[1]首都医科大学附属北京儿童医院康复科,北京100045 [2]北京中医药大学第三附属医院ICU,北京100029

出　　处：《中国医学装备》2015年第11期96-99,共4页China Medical Equipment

摘　　要：目的:在脉搏指示连续心输出量(PICCO)监测下,研究人参四逆汤早期目标治疗感染性休克的临床疗效。方法:选取44例感染性休克患者,随机将其分为观察组(23例)和对照组(21例)。安装PICCO装置,对照组采用常规治疗,观察组在常规治疗的基础上给予人参四逆汤;统计两组治疗前、后心率(HR)、有创平均动脉压(IMAP)、中心静脉压(CVP)、血氧饱和度(Sp O2)、血乳酸(Lac)、心排血指数(CI)、胸腔内血容量指数(ITBVI)以及外周血管阻力指数(SVRI)。结果:治疗前两组患者的HR、IMAP、CVP、Sp O2、Lac、CI、ITBVI以及SVRI水平相比,差异无统计学意义(P>0.05);治疗6 h后,观察组Lac显著低于对照组,差异有统计学意义(P<0.05)。结论:人参四逆汤可用于早期目标治疗感染性休克,进一步改善组织灌注。Objective： To evaluate the effect of Ginseng-Sini in early goal directed treatment septic shock under PICCO. Methods： Forty four patents with septic shock were randomly divided into control group, which treated with Ginseng-Sini on the basis of routine treatment under PICCO, observation groups, which treated with only the basis of routine treatment under PICCO. Before and after the drugs were given for 6 hours, HR, IMAP, CVP, Sp O2, Lac, CI, ITBVI, SVRI were monitored. Results： Before treatment, HR, IMAP, CVP, Sp O2, Lac, CI, ITBVI, SVRI of the observation group were not different from the control group（P〉0.05）; after 6 hours of treatment, CI of the observation group were higher than that of the control group（P〉0.05）. Conclusion： Ginseng-Sini in the early goal directed of septic shock is effective, especially in improving tissue perfusion.

关 键 词：脉搏指示连续心输出量 人参四逆汤 感染 休克 

分 类 号：R944.61[医药卫生—药剂学]