Probing hepatocyte heterogeneity  

作　　者：Ben Z Stanger 

机构地区：[1]Departments of Medicine and Cell and Developmental Biology, BRB 11/111, Rm. 512, 421 Curie Boulevard, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA19104

出　　处：《Cell Research》2015年第11期1181-1182,共2页细胞研究（英文版）

摘　　要：To maintain homeostasis, organs replace cells lost through normal cellular turnover, often through the straightforward replication of exist- ing cells. A recent paper in Nature shows that cells in the liver are not equivalent when it comes to their replicative capacity; rather, a sub- set of hepatocytes defined by the maintenance of active Wnt signaling bears the brunt of responsibility for maintaining liver mass.

关 键 词：细胞异质性 肝细胞 体内平衡 WNT 复制 

分 类 号：Q345.2[生物学—遗传学] Q813.11