磁共振检查在脑室扩张胎儿产前诊断中的作用  

Role of magnetic resonance imaging in prenatal diagnosis of fetal ventriculomegaly

作　　者：刘春敏[1] 蒋玲[2] 方爱华[3] 林育[1] 张艳[1] 王彦林[1] 

机构地区：[1]上海交通大学附属国际和平妇幼保健院产前诊断中心,上海200030 [2]上海交通大学附属国际和平妇幼保健院放射科,上海200030 [3]上海交通大学附属国际和平妇幼保健院计划生育科,上海200030

出　　处：《生殖与避孕》2015年第11期750-755,共6页Reproduction and Contraception

摘　　要：目的:探讨磁共振成像(MRI)在超声提示脑室扩张胎儿产前诊断中的作用。方法:选择因超声提示单纯性脑室扩张而行MRI检查者,对MRI结果进行分析并随访妊娠结局。结果:1 MRI结果的准确性:入组病例MRI对超声的总补充诊断率为15.4%(38/247),其中脑积水11例,脑室扩张伴脑出血3例,脑室扩张伴胼胝体发育不全(ACC)9例,室管膜下囊肿(或蛛网膜囊肿)9例,DandyWalker等其他类型畸形6例。2胎儿脑室扩张的宫内转归及新生儿预后:63.2%(24/38)有结构畸形者选择引产,均未见染色体核型异常。正常分娩新生儿155例,新生儿随访无异常神经系统表现。结论:对于脑室扩张,尤其是重度脑室扩张,MRI对于超声有极高的补充诊断价值。Objective： To investigate the role of magnetic resonance imaging （MRI） in prenatal diagnosis of fetal ventriculomegaly. Methods： A retrospective analysis was performed in 247 pregnant women with simple ventriculomegaly which were diagnosed by ultrasound underwent fetal MRI. Results： 1） The accuracy of MRI： MRI provided an additional diagnostic rate of 15.4% （38/247） including hydrocephalus （11 cases）, ventriculomegaly with intracerebral hemorrhage （3 cases）, ventriculomegaly with agenesis of the corpus callosum （ACC） 9 cases, subependymal cyst or arachnoid cyst （9 cases）, Dandy-Walker malformation and other central nervous system （CNS） abnormalities （6 cases）. 2） Intrauterine outcome and neonatal prognosis of ventriculomegaly： 27 CNS abnormalities cases （63.2%） selected termination of pregnancy. No case with aneuploidy malformation was found. Neurology follow-up in 155 babies of normal delivery were normal. Conclusion： MRI is an indispensable complementary diagnostic method for fetal ventriculomegaly diagnostic by prenatal ultrasound scan, especially for severe ventriculomegaly cases.

关 键 词：脑室扩张 磁共振成像 预后 

分 类 号：R445.2[医药卫生—影像医学与核医学] R714.5[医药卫生—诊断学]