基于聚多巴胺的表面改性方法研究现状  

Research Status of the Surface Modification Method Based on Polydopamine

作　　者：陶彩虹[1] 马阜生 刘宝勇[1] 赵萌萌[1] 

机构地区：[1]兰州交通大学化学与生物工程学院,兰州730070

出　　处：《化学通报》2015年第11期983-990,共8页Chemistry

基　　金：甘肃省高等学校基本科研业务费项目;甘肃省高校科研项目(2013A-042);兰州交通大学青年基金项目资助

摘　　要：多巴胺具有与贻贝粘附蛋白类似的性能。它可以沉积在几乎所有物质表面对其进行改性,且能与氨基、巯基、金属离子等官能团反应,所以将多巴胺修饰在材料表面不但可以赋予材料表面依赖于聚多巴胺(PDA)的仿生特性,而且PDA的反应活性为材料表面的二次修饰提供了理想的平台。这种基于PDA的表面修饰方法不但简单、绿色且适用性非常广,可应用于化学、生物、医药、材料等多个领域。本文从多巴胺的结构以及聚合、粘附机理研究入手,对近几年在材料表面修饰PDA,且以其为平台再二次修饰的报道进行了归纳总结,进一步认识和理解了多巴胺的性能,并为设计和构建新型的、高性能化的PDA仿生功能材料提供思路,推动研究者们在此基础上将PDA应用于更多的领域,使其向着绿色化和多样化方向发展。Dopamine has the similar properties with the mussel adhesive proteins. It can be virtually attached to all types of material surfaces,including highly hydrophobic polymers. And the polydopamine（ PDA） coating was found to be an extremely versatile platform for secondary reactions,leading to tailoring of the coatings for diverse functional uses. The metal binding ability of catechols present in the PDA coating was exploited to deposit adherent and uniform metal coatings onto substrates by electroless metallization. And PDA coatings also support a variety of reactions with organic species for the creation of functional organic ad-layers. With these benefits,PDA is not restricted to use as a coating material and has been rapidly incorporated into a wide range of applications across the chemical,biological,medical,and materials sciences. This paper offers readers an overall framework about the surface modification method based on PDA and gives a further impulse to scientists working in related fields to enter this field.

关 键 词：多巴胺 表面改性 复合材料 纳米材料 核壳结构 

分 类 号：TQ316.6[化学工程—高聚物工业]