Synthesis of Terphenyl Derivatives by Pd-Catalyzed Suzuki-Miyaura Reaction of Dibromobenzene Using 2N20-Salen as a Ligand in Aqueous Solution  

作　　者：Ningning Gu Yashuai Liu Ping Liu Xiaowei Ma Liu Yan Bin Dai 

机构地区：[1]School of Chemistry and Chemical Engineering, Key Laboratory for Green Processing of Chemical Engineering of Xinjiang Bingtuan, Shihezi University, Shihezi, Xinjiang 832003, China

出　　处：《Chinese Journal of Chemistry》2015年第10期1189-1193,共5页中国化学（英文版）

摘　　要：A simple and efficient catalytic system for Na2PdC14 catalyzing the Suzuki-Miyaura reaction of dibromoben- zene and arylboronic acid has been developed by using 2N2O-salen as a ligand in H2O/EtOH （V ： V=4 ： 1） at 100 ℃. Using this method, the reactions of substrates containing sterically demanding ortho substituents （e.g. dibromo- benzene and/or arylboronic acids） proceeded efficiently, with the corresponding terphenyl derivatives being pro- duced in moderate to excellent yields. Furthermore, this method offers interesting features for the multi-gram scale synthesis of terphenyl compound.A simple and efficient catalytic system for Na2PdC14 catalyzing the Suzuki-Miyaura reaction of dibromoben- zene and arylboronic acid has been developed by using 2N2O-salen as a ligand in H2O/EtOH （V ： V=4 ： 1） at 100 ℃. Using this method, the reactions of substrates containing sterically demanding ortho substituents （e.g. dibromo- benzene and/or arylboronic acids） proceeded efficiently, with the corresponding terphenyl derivatives being pro- duced in moderate to excellent yields. Furthermore, this method offers interesting features for the multi-gram scale synthesis of terphenyl compound.

关 键 词：TERPHENYLS synthesis 2N2O-salen PALLADIUM CATALYZE Suzuki-Miyaura reaction 

分 类 号：O625.13[理学—有机化学] TQ246[理学—化学]