尿道下裂患者术后抑郁情况及抑郁相关因素分析  

Incidence of Depression and Its Related Factors in Hypospadias Patients after Surgical Treatment

作　　者：杨明根[1] 郑周达[1] 许振强[1] 林海利[1] 庄志明[1] 张朝贤[1] 

机构地区：[1]福建医科大学附属漳州市医院泌尿外科,福建漳州363000

出　　处：《中国循证医学杂志》2015年第11期1254-1257,共4页Chinese Journal of Evidence-based Medicine

摘　　要：目的分析尿道下裂患者术后抑郁症状的发生情况和相关影响因素。方法 2015年1月至6月,选择1990年1月至1994年12月在福建医科大学附属漳州市医院行手术治疗的尿道下裂患者,并按1∶1匹配同期年龄和心理健康的成年人。采用Zung氏抑郁自评量表和自制的心理调查表对纳入患者的抑郁情况进行调查,并对抑郁相关影响因素进行分析。结果共纳入80例经手术治疗的尿道下裂患者和80例健康对照。两组男性第二性征发育均正常,双侧睾丸发育正常,测定血清睾酮水平无明显异常,术后阴茎长度、粗细与对照组比较均无明显差异。尿道下裂患者抑郁症状发生率为45.0%,而对照组仅为6.3%,其差异有统计学意义(χ2=6.632,P=0.01)。多元逐步回归分析结果显示,阴茎和阴囊外观满意度(F=16.210 3,P=0.001)、性生活满意度(F=4.621 2,P=0.036)和性功能(F=4.103 2,P=0.043)是影响尿道下裂患者术后抑郁症状的独立危险因素。结论尿道下裂患者术后常发生抑郁症状,主要影响因素为阴茎和阴囊外观满意度、性生活满意度和性功能。Objectiv To investigate the incidence of depression and its etiological factors in patients with hypospadias after operation. Methods From January to June 2015, we investigated the incidence of depression symptoms among patients with hypospadias after surgical treatment from January 1990 to December 1994 in Zhangzhou Affiliated Hospital of Fujian Medical University, and we matched them with mentally healthy adults of the same age to 1：1 ratio. Zung Self-Rating Depression Scale and Correlation Factor Questionnaire were used to investigate and analyze the related factors of depression symptoms between the patients with hypospadias and the healthy males. Results A total of 80 patients with hypospadias after surgical treatment and 80 healthy males as control were included. There were no significant differences in male secondary sexual development, testis development, serum testosterone levels and postoperative length and girth of the penis in two groups. The incidence rate of depression symptoms was 45.0% （16/80） in the hypospadias patients after operation, extremely significantly higher than 6.3% （5/80） in the control group （X2=6.632, P=0.01）. The result of multiple stepwise regression analysis showed that the main risk factors of depression symptoms were worries about dissatisfaction with penile and scrotal appearance （F=16.210 3, P=0.001）, sexual satisfaction （F=4.621 2, P=0.036） and sexual function （F=4.103 2, P=0.043）. Conclusion Symptoms of depression often occur in hypospadias patients after operation, and the major etiological factors are dissatisfaction with penile and scrotal appearance, sexual satisfaction and sexual function.

关 键 词：尿道下裂 抑郁 抑郁自评量表 问卷调查 

分 类 号：R699.6[医药卫生—泌尿科学]